- Chemical Name:2-(Chloromethyl)pyridin-1-ium chloride
- CAS No.:6959-47-3
- Molecular Formula:C6H7Cl2N
- Molecular Weight:164.034
- Hs Code.:29333990
- Mol file:6959-47-3.mol
Synonyms:2-(chloromethyl)pyridin-1-ium chloride;NS00043720
Synonyms:2-(chloromethyl)pyridin-1-ium chloride;NS00043720
98%, *data from raw suppliers
2-(Chloromethyl)pyridine hydrochloride *data from reagent suppliers
There total 7 articles about 2-(Chloromethyl)pyridin-1-ium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
Reference yield: 100.0%
Reference yield: 51.0%
Reference yield:
The research focuses on the synthesis, optical properties, and protonation of chlorophyll-a (Chl-a) derivatives that have a 2-(2/3/4-pyridyl)ethenyl group at the C3 position. The derivatives were synthesized using the Wittig reaction on methyl pyropheophorbide-d, which involved reactants such as 2/3/4-(chloromethyl)pyridine hydrochloride and triphenylphosphine. The resulting olefins were then subjected to catalytic hydrogenation using PtO2 in a mixed solvent of acetone and ethanol to yield the corresponding regioisomers. The optical properties of these derivatives were analyzed using visible absorption and fluorescence emission spectra, with the longest wavelength (Qy) maxima shifting bathochromically based on the linker between the chlorin and pyridyl moieties. Protonations were conducted by titrating the synthetic chlorophyll-pyridine conjugates with trifluoroacetic acid in chloroform, and the resulting visible spectral changes indicated the order of protonation. The analyses included the determination of association constants, high-resolution mass spectrometry (HRMS), and nuclear magnetic resonance (NMR) spectroscopy.