Technology Process of C21H22N2
There total 8 articles about C21H22N2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-Methyl-4-piperidone; 5-methyl-2-phenyl-N-(propan-2-ylidene)indolin-1-amine;
With
hydrogenchloride;
In
ethanol; isopropyl alcohol;
at 90 ℃;
for 15h;
With
sodium hydroxide;
In
ethanol; isopropyl alcohol;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: phosphoric acid / 2 h / 100 °C
1.2: 20 °C
2.1: sodium cyanoborohydride; acetic acid / 4 h / 20 °C
3.1: hydrogenchloride; sodium nitrite / water / 1.08 h / 0 - 20 °C
4.1: zinc; ammonium chloride / 0.5 h / 0 °C
5.1: hydrogenchloride / isopropyl alcohol; ethanol / 15 h / 90 °C
5.2: 20 °C
With
hydrogenchloride; phosphoric acid; sodium cyanoborohydride; ammonium chloride; acetic acid; zinc; sodium nitrite;
In
ethanol; water; isopropyl alcohol;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sulfuric acid / 1,4-dioxane / 6 h / 100 °C
2.1: phosphoric acid / 2 h / 100 °C
2.2: 20 °C
3.1: sodium cyanoborohydride; acetic acid / 4 h / 20 °C
4.1: hydrogenchloride; sodium nitrite / water / 1.08 h / 0 - 20 °C
5.1: zinc; ammonium chloride / 0.5 h / 0 °C
6.1: hydrogenchloride / isopropyl alcohol; ethanol / 15 h / 90 °C
6.2: 20 °C
With
hydrogenchloride; phosphoric acid; sulfuric acid; sodium cyanoborohydride; ammonium chloride; acetic acid; zinc; sodium nitrite;
In
1,4-dioxane; ethanol; water; isopropyl alcohol;
1.1: Fischer Indole Synthesis;
