Technology Process of 3-benzylsulfonylindol-1-yl-acetic acid
There total 5 articles about 3-benzylsulfonylindol-1-yl-acetic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
ethyl 3-benzylsulfonylindol-1-ylacetate;
With
water; sodium hydroxide;
In
methanol;
at 20 ℃;
for 2h;
With
hydrogenchloride;
In
water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium iodide; thiourea; iodine / water; methanol / 2 h / 20 °C
1.2: 0.5 h / 85 °C
1.3: 20 °C
2.1: sodium hydride / 1,4-dioxane; mineral oil / 0.17 h
2.2: 0.17 h / 20 °C
3.1: sodium hydrogencarbonate; Oxone / water; acetone / 18 h
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h
4.2: 5 h
5.1: sodium hydroxide; water / methanol / 2 h / 20 °C
With
Oxone; water; iodine; sodium hydride; sodium hydrogencarbonate; thiourea; potassium iodide; sodium hydroxide;
In
1,4-dioxane; methanol; water; N,N-dimethyl-formamide; acetone; mineral oil;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydrogencarbonate; Oxone / water; acetone / 18 h
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h
2.2: 5 h
3.1: sodium hydroxide; water / methanol / 2 h / 20 °C
With
Oxone; water; sodium hydride; sodium hydrogencarbonate; sodium hydroxide;
In
methanol; water; N,N-dimethyl-formamide; acetone; mineral oil;
