3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

Base Information

Chemical Name:3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid
CAS No.:1333896-52-8
Molecular Formula:C₁₄H₁₅NO₄
Molecular Weight:261.277
Hs Code.:

Synonyms:3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

Suppliers and Price of 3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

There total 5 articles about 3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1333896-51-7
ethyl 3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoate

: 1333896-52-8
3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1021/jm200640v

Reference yield:

: 140472-69-1
3-bromo-5-hydroxy-benzoic acid

: 1333896-52-8
3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 100 °C / Inert atmosphere

2: palladium diacetate; sodium carbonate; ruphos / ethanol / 48 h / 100 °C / Inert atmosphere

3: water; lithium hydroxide / tetrahydrofuran / 16 h / 20 °C

With water; palladium diacetate; sodium carbonate; potassium carbonate; lithium hydroxide; ruphos; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm200640v

Reference yield:

: 1229442-68-5
ethyl 3-bromo-5-ethoxybenzoate

: 1333896-52-8
3-(3,5-dimethylisoxazol-4-yl)-5-ethoxybenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl acetamide; potassium acetate; palladium dichloride / 44 h / 130 °C / Inert atmosphere

2: water; lithium hydroxide / tetrahydrofuran / 16 h / 20 °C

With N,N-dimethyl acetamide; water; potassium acetate; palladium dichloride; lithium hydroxide; In tetrahydrofuran;
DOI:10.1021/jm200640v