Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate

Base Information

• Chemical Name: Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate
• CAS No.: 322392-78-9
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.283
• Mol file: 322392-78-9.mol

Synonyms:Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate

Chemical Property of Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate

There total 2 articles about Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

methyl 2-aminoisobutyrate hydrochloride (15028-41-8) + α-bromoacetophenone (70-11-1) → Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate (322392-78-9)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.1016/j.tetlet.2009.04.036

Reference yield:

→ Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate (322392-78-9)

Guidance literature:

Reference yield: 88.0%

4-(aminomethyl)pyridine (3731-53-1) + Methyl 2-(2-oxo-2-phenylethyl)aminoisobutyrate (322392-78-9) → C18H21N3O (1172602-45-7)

Guidance literature:

With sodium cyanoborohydride; acetone; In methanol; at 50 ℃;

DOI:10.1016/j.tetlet.2009.04.036

upstream raw materials:

methyl 2-aminoisobutyrate hydrochloride

α-bromoacetophenone

Downstream raw materials:

C₁₈H₂₁N₃O

C₂₁H₂₃N₃O

C₂₀H₂₁N₃O

C₁₉H₂₈N₂O₃

Refernces

• 1、 -. "NOVEL THIAZINE OR PYRAZINE DERIVATIVES". . . Retrieved 2008/06/13.