(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

Base Information

Chemical Name:(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine
CAS No.:1218918-79-6
Molecular Formula:C₁₆H₂₆FNO₃SSi
Molecular Weight:359.537
Hs Code.:

Synonyms:(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

Suppliers and Price of (2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

Chemical Property:

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Technology Process of (2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

There total 1 articles about (2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1218918-78-5
2-[(2R)-1-[(4-fluorophenyl)sulfonyl]aziridin-2-yl]ethanol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1218918-79-6
(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

Guidance literature:: With 1H-imidazole; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield:

: 1912-33-0
Indole-3-acetic acid methyl ester

: 1218918-79-6
(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

: 74-88-4
methyl iodide

: 1218918-80-9
C₂₈H₃₉FN₂O₅SSi

Guidance literature:: Indole-3-acetic acid methyl ester; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;

(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine; In N,N-dimethyl-formamide;

methyl iodide; In N,N-dimethyl-formamide; for 1h;

Reference yield:

: 169030-84-6
methyl (1H-pyrrolo[2,3-b]pyridin-3-yl)acetate

: 1218918-79-6
(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine

: 1219011-07-0
methyl [1-((2R)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-{[(4-fluorophenyl)sulfonyl]amino}butyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]acetate

Guidance literature:: methyl (1H-pyrrolo[2,3-b]pyridin-3-yl)acetate; With sodium hydride; N,N-dimethyl-formamide; In mineral oil; at 20 ℃; for 0.166667h;

(2R)-2-(2-[[tert-butyl(dimethyl)silyl]oxy]ethyl)-1-(4-fluorobenzenesulfonyl)aziridine; With N,N-dimethyl-formamide; In mineral oil; at 20 ℃; for 0.5h;