Technology Process of (3R,4S)-5-azido-3,4-bisbenzyloxy-pent-1-ene
There total 4 articles about (3R,4S)-5-azido-3,4-bisbenzyloxy-pent-1-ene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran;
DOI:10.1021/cb5003416
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Cumene hydroperoxide / titanium(IV) isopropylate; L-(+)-diisopropyl tartrate / dichloromethane / 48 h / -35 °C / Molecular sieve
2: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / -15 - 20 °C / Inert atmosphere
3: sodium azide; ammonium chloride / water; methanol / 96 h
4: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere
With
sodium azide; Cumene hydroperoxide; sodium hydride; ammonium chloride;
titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran; methanol; dichloromethane; water; mineral oil;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium azide; ammonium chloride / water; methanol / 96 h
2.1: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / 0 - 20 °C / Inert atmosphere
2.2: 20 °C
With
sodium azide; sodium hydride; ammonium chloride;
tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran; methanol; water; mineral oil;
