ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate

Base Information

• Chemical Name: ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
• CAS No.: 1262841-96-2
• Molecular Formula: C₂₁H₁₈N₂O₃
• Molecular Weight: 346.386
• Mol file: 1262841-96-2.mol

Synonyms:ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate

Chemical Property of ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate

There total 15 articles about ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C28H28N2O5S (1262842-23-8) → ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate (1262841-96-2)

Guidance literature:

With oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dimethyl sulfoxide; at 20 ℃; for 4h;

DOI:10.1002/ejoc.201001153

Reference yield: 83.0%

ethyl 1-(4-methoxyphenyl)-1,2,3,4-tetrahydro-β-carboline-3-carboxylate → ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate (1262841-96-2)

Guidance literature:

With sulfur; In 5,5-dimethyl-1,3-cyclohexadiene; for 8h; Reflux;

DOI:10.1039/c5md00312a

Reference yield: 79.0%

C33H31N2O3P (156046-90-1) + 4-methoxy-benzaldehyde (123-11-5) → ethyl 1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate (1262841-96-2)

Guidance literature:

With 1-methyl-3-methylimidazol-3-ium tetrafluoroborate; at 200 ℃; for 0.25h; Microwave irradiation; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.03.049

upstream raw materials:

C₂₈H₂₈N₂O₅S

C₃₃H₃₁N₂O₃P

4-methoxy-benzaldehyde

1-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid

Downstream raw materials:

1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carbaldehyde

ethyl 9-methyl-1-(4-methoxyphenyl)-β-carboline-3-carboxylate