4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone

Base Information

• Chemical Name: 4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone
• CAS No.: 75088-15-2
• Molecular Formula: C₁₈H₁₆O₆
• Molecular Weight: 328.321
• Mol file: 75088-15-2.mol

Synonyms:4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone

Chemical Property of 4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone

There total 1 articles about 4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

methanol (67-56-1) + sofalcone (64506-49-6) → 4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone (75088-15-2)

Guidance literature:

With hydrogenchloride; for 2h; Heating;

DOI:10.1248/cpb.33.1327

Reference yield: 82.0%

4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone (75088-15-2) → 4,4'-dihydroxy-2'-(methoxycarbonylmethoxy)dihydrochalcone (75088-16-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1248/cpb.33.1327

Reference yield:

4,4'-dihydroxy-2'-methoxycarbonylmethoxychalcone (75088-15-2) → 2'-carboxymethoxy-4-hydroxy-4'-(3-methyl-2-butenyloxy)dihydrochalcone (75088-23-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / H₂ / Pd-C (10percent) / methanol

2: 70 percent / K₂CO₃ / acetone / 4 h / Ambient temperature

3: 0.5 g / KOH / acetone; H₂O / 0.5 h / Heating

With potassium hydroxide; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; water; acetone;

DOI:10.1248/cpb.33.1327

upstream raw materials:

methanol

sofalcone

Downstream raw materials:

4,4'-dihydroxy-2'-(methoxycarbonylmethoxy)dihydrochalcone

2'-carboxymethoxy-4-hydroxy-4'-(3-methyl-2-butenyloxy)dihydrochalcone

4-hydroxy-2'-methoxycarboxymethoxy-4'-(3-methyl-2-butenyloxy)dihydrochalcone

2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)dihydrochalcone

Refernces