(R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

Base Information

Chemical Name:(R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide
CAS No.:1428526-95-7
Molecular Formula:C₁₇H₁₉BrFNOS
Molecular Weight:384.312
Hs Code.:

Synonyms:(R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

Suppliers and Price of (R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

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Chemical Property of (R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

Chemical Property:

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Technology Process of (R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

There total 3 articles about (R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 1187992-96-6
4-hydroxy-2-(1H-pyrazol-1-yl)pyrimidine-5-carboxylic acid

: 336105-24-9
(R)-(-)-N-[(1E)-(4-bromophenyl)methylene]-2-methyl-2-propanesulfinamide

: 1428526-95-7
(R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

Guidance literature:: 4-hydroxy-2-(1H-pyrazol-1-yl)pyrimidine-5-carboxylic acid; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h;

(R)-(-)-N-[(1E)-(4-bromophenyl)methylene]-2-methyl-2-propanesulfinamide; In tetrahydrofuran; at -78 ℃; for 1h;

Reference yield: 31.0%

: 460-00-4
1-Bromo-4-fluorobenzene

: 336105-24-9
(R)-(-)-N-[(1E)-(4-bromophenyl)methylene]-2-methyl-2-propanesulfinamide

: 1428526-95-7
(R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

Guidance literature:: 1-Bromo-4-fluorobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃;

(R)-(-)-N-[(1E)-(4-bromophenyl)methylene]-2-methyl-2-propanesulfinamide; In tetrahydrofuran; at -78 ℃;

Reference yield:

: 1122-91-4
4-bromo-benzaldehyde

: 1428526-95-7
(R)-N-((R)-(4-bromophenyl)(4-fluorophenyl)methyl)-2-methylpropane-2-sulfinamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridinium p-toluenesulfonate; copper(II) sulfate / dichloromethane / 37 °C

2.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C

2.2: 1 h / -78 °C

With n-butyllithium; pyridinium p-toluenesulfonate; copper(II) sulfate; In tetrahydrofuran; dichloromethane;