Acetamide, 2-(triphenylphosphoranylidene)-

Base Information

• Chemical Name: Acetamide, 2-(triphenylphosphoranylidene)-
• CAS No.: 38821-11-3
• Molecular Formula: C20H18NOP
• Molecular Weight: 319.343
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID30192083
• Nikkaji Number: J55.334D
• Wikidata: Q83064690
• Mol file: 38821-11-3.mol

Synonyms:38821-11-3;ACETAMIDE, 2-(TRIPHENYLPHOSPHORANYLIDENE)-;Triphenylphosphonium carbamoylmethylide;2-(Triphenylphosphoranylidene)acetamide;(Triphenylphosphoranylidene)acetamide;BRN 0803830;Phosphonium, triphenyl-, carbamoylmethylide;SCHEMBL5694513;DTXSID30192083;C20-H18-N-O-P;carbamoylmethylene triphenylphosphorane;carbamoylmethylene-triphenylphosphorane;2-(triphenyl-lambda5-phosphanylidene)acetamide

Chemical Property of Acetamide, 2-(triphenylphosphoranylidene)-

Chemical Property:

• Vapor Pressure: 1.96E-10mmHg at 25°C
• Boiling Point: 507.8°C at 760 mmHg
• Flash Point: 260.9°C
• PSA: 52.90000
• Density: 1.2g/cm³
• LogP: 2.96830
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 319.112601195
• Heavy Atom Count: 23
• Complexity: 388

Purity/Quality:

99% ^*data from raw suppliers

2-(TRIPHENYLPHOSPHORANYLIDENE)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=CC(=O)N)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Acetamide, 2-(triphenylphosphoranylidene)-

There total 4 articles about Acetamide, 2-(triphenylphosphoranylidene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

(2-amino-2-oxo-ethyl)triphenyl-phosphonium chloride (25361-54-0) → 2-(triphenylphosphoranylidene)acetamide (38821-11-3)

Guidance literature:

With sodium hydroxide; at 4 ℃;

DOI:10.1039/b211564f

Reference yield:

triphenylphosphine (603-35-0) → 2-(triphenylphosphoranylidene)acetamide (38821-11-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / various solvent(s) / 16 h / 100 °C

2: 79 percent / aq. NaOH / 4 °C

With sodium hydroxide; In various solvent(s);

DOI:10.1039/b211564f

Reference yield:

triphenylphosphine (603-35-0) → 2-(triphenylphosphoranylidene)acetamide (38821-11-3)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 10 h / 80 °C

2: sodium hydrogencarbonate / tetrahydrofuran / 0.5 h / 20 °C

With sodium hydrogencarbonate; In tetrahydrofuran; toluene;

upstream raw materials:

(2-amino-2-oxo-ethyl)triphenyl-phosphonium chloride

triphenylphosphine

Downstream raw materials:

β-Carbomethoxy-cis-cinnamamid

non-2-enamide

acetamidomethylene-3 benzyl-6 piperazinedione-2,5

5-(carbamoylmethyl)uridine