(2-amino-2-oxoethyl)(triphenyl)phosphonium chloride

Base Information

• Chemical Name: (2-amino-2-oxoethyl)(triphenyl)phosphonium chloride
• CAS No.: 25361-54-0
• Molecular Formula: C20H19 N O P . Cl
• Molecular Weight: 355.804
• Mol file: 25361-54-0.mol

Synonyms:(Carbamoylmethyl)triphenylphosphoniumchloride (6CI); Phosphonium, (2-amino-2-oxoethyl)triphenyl-, chloride (9CI);Phosphonium, (carbamoylmethyl)triphenyl-, chloride (8CI)

Chemical Property of (2-amino-2-oxoethyl)(triphenyl)phosphonium chloride

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of (2-amino-2-oxoethyl)(triphenyl)phosphonium chloride

There total 2 articles about (2-amino-2-oxoethyl)(triphenyl)phosphonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

triphenylphosphine (603-35-0) + Chloroacetamide (79-07-2) → (2-amino-2-oxo-ethyl)triphenyl-phosphonium chloride (25361-54-0)

Guidance literature:

In nitromethane; at 105 ℃; for 19h; Schlenk technique;

DOI:10.1007/s00706-015-1599-0

Reference yield:

→ (2-amino-2-oxo-ethyl)triphenyl-phosphonium chloride (25361-54-0)

Guidance literature:

/BRN= 3812975/;

DOI:10.1039/jr9590003874

Reference yield: 90.0%

5-bromo-2-nitrobenzaldehyde (20357-20-4) + (2-amino-2-oxo-ethyl)triphenyl-phosphonium chloride (25361-54-0) → (E)-3-(5-bromo-2-nitrophenyl)acrylamide (1426942-96-2)

Guidance literature:

(2-amino-2-oxoethyl)(triphenyl)phosphonium chloride; With potassium tert-butylate; In methanol; for 0.333333h; Inert atmosphere; Cooling with ice;

5-bromo-2-nitrobenzaldehyde; In methanol; at -2 ℃; for 0.75h; Inert atmosphere;

DOI:10.1002/chem.201203005

upstream raw materials:

triphenylphosphine

Chloroacetamide

Downstream raw materials:

2-(triphenylphosphoranylidene)acetamide

triphenyl(thiocarbamoylmethylene)phosphorane

1.3.5-Tris-(cyclohexylcarbonyl)-benzol

2,6-dicyclohexylpyridine