(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)aMino]-5-[[iMino(nitroaMino)Methyl]aMino]-1-oxopentyl]-4-Methyl-2-piperidinecarboxylic Acid Benzyl Ester

Base Information

Chemical Name:(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)aMino]-5-[[iMino(nitroaMino)Methyl]aMino]-1-oxopentyl]-4-Methyl-2-piperidinecarboxylic Acid Benzyl Ester
CAS No.:367952-82-7
Molecular Formula:C₂₅H₃₈N₆O₇
Molecular Weight:534.613
Hs Code.:
Mol file:367952-82-7.mol

(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)aMino]-5-[[iMino(nitroaMino)Methyl]aMino]-1-oxopentyl]-4-Methyl-2-piperidinecarboxylic Acid Benzyl Ester

Synonyms:C₂₅H₃₈N₆O₇

Suppliers and Price of (2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)aMino]-5-[[iMino(nitroaMino)Methyl]aMino]-1-oxopentyl]-4-Methyl-2-piperidinecarboxylic Acid Benzyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylicAcidBenzylEster
10mg
$ 195.00

TRC
(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylicAcidBenzylEster
100mg
$ 1540.00

Medical Isotopes, Inc.
(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylicAcidBenzylEster
10 mg
$ 675.00

Total 3 raw suppliers

Chemical Property of (2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)aMino]-5-[[iMino(nitroaMino)Methyl]aMino]-1-oxopentyl]-4-Methyl-2-piperidinecarboxylic Acid Benzyl Ester

Chemical Property:

Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

98% ^*data from raw suppliers

(2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylicAcidBenzylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (2R,4R)-Argatroban (A769000) intermediate.

Technology Process of (2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)aMino]-5-[[iMino(nitroaMino)Methyl]aMino]-1-oxopentyl]-4-Methyl-2-piperidinecarboxylic Acid Benzyl Ester

There total 5 articles about (2R,4R)-1-[(2S)-2-[(tert-Butyloxycarbonyl)aMino]-5-[[iMino(nitroaMino)Methyl]aMino]-1-oxopentyl]-4-Methyl-2-piperidinecarboxylic Acid Benzyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 626-58-4
4-methylpiperidin

: 367952-82-7
C₂₅H₃₈N₆O₇

Guidance literature:: Multi-step reaction with 4 steps

1.1: 100 percent / Et₃N / CH₂Cl₂ / 0 - 20 °C

2.1: s-BuLi; TMEDA / diethyl ether / -90 °C

2.2: 35 percent / diethyl ether / -90 - 20 °C

3.1: 99 percent / HCl / ethyl acetate / 0 - 20 °C

With hydrogenchloride; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; triethylamine; In diethyl ether; dichloromethane; ethyl acetate;
DOI:10.1016/S0960-894X(01)00351-1

Reference yield:

: 123387-50-8
4-methylpiperidine-1-carboxylic acid tert-butyl ester

: 367952-82-7
C₂₅H₃₈N₆O₇

Guidance literature:: Multi-step reaction with 3 steps

1.1: s-BuLi; TMEDA / diethyl ether / -90 °C

1.2: 35 percent / diethyl ether / -90 - 20 °C

2.1: 99 percent / HCl / ethyl acetate / 0 - 20 °C

With hydrogenchloride; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In diethyl ether; ethyl acetate;
DOI:10.1016/S0960-894X(01)00351-1

Reference yield:

: 339183-92-5
benzyl trans-N-Boc-4-methylpipecolic acid ester

: 367952-82-7
C₂₅H₃₈N₆O₇

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / HCl / ethyl acetate / 0 - 20 °C

With hydrogenchloride; In ethyl acetate;
DOI:10.1016/S0960-894X(01)00351-1