(R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

Base Information

Chemical Name:(R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate
CAS No.:1392008-14-8
Molecular Formula:C₁₅H₂₁FN₂O₃
Molecular Weight:296.342
Hs Code.:

Synonyms:(R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

Suppliers and Price of (R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

There total 1 articles about (R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1813-93-0
ethyl 2-(2-fluorophenyl)-2-oxoacetate

: 108199-32-2
tert-butylhydrazone of formaldehyde

: 1392008-14-8
(R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

Guidance literature:: With (R)-1-(3,5-bis-trifluoromethylphenyl)-3-{2'-[3-(3,5-bis-trifluoromethylphenyl)ureido]-5,6,7,8,5',6',7',8'-octahydro[1,1']binaphthalenyl-2-yl}-urea; In toluene; at -45 ℃; for 8h; optical yield given as %ee; enantioselective reaction;
DOI:10.1021/ja305209w

Reference yield:

: 1392008-14-8
(R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

: C₁₁H₁₁FO₄

Guidance literature:: With hydrogenchloride; In diethyl ether; water; at 0 ℃;
DOI:10.1021/ja305209w

Reference yield:

: 1392008-14-8
(R,E)-ethyl 3-(tert-butyldiazenyl)-2-(2-fluorophenyl)-2-hydroxypropanoate

: 1392008-24-0
(R)-ethyl 2-(2-fluorophenyl)-2,3-dihydroxypropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / diethyl ether; water / 0 °C

2: tetrabutylammonium borohydride / dichloromethane / 1 h / 20 °C

With hydrogenchloride; tetrabutylammonium borohydride; In diethyl ether; dichloromethane; water;
DOI:10.1021/ja305209w