1-benzyl-2,5,6-trichlorobenzimidazole

Base Information

• Chemical Name: 1-benzyl-2,5,6-trichlorobenzimidazole
• CAS No.: 142372-26-7
• Molecular Formula: C₁₄H₉Cl₃N₂
• Molecular Weight: 311.598
• Mol file: 142372-26-7.mol

Synonyms:1-benzyl-2,5,6-trichlorobenzimidazole

Chemical Property of 1-benzyl-2,5,6-trichlorobenzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-2,5,6-trichlorobenzimidazole

There total 4 articles about 1-benzyl-2,5,6-trichlorobenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

benzyl bromide (100-39-0) + 2,5,6-trichloro-1H-benzo[d]imidazole (16865-11-5) → 1-benzyl-2,5,6-trichlorobenzimidazole (142372-26-7)

Guidance literature:

With sodium hydroxide; In acetonitrile; Heating;

DOI:10.1021/jm970559i

Reference yield:

water (7732-18-5) + benzyl bromide (100-39-0) + potassium carbonate (584-08-7) + 2,5,6-trichloro-1H-benzo[d]imidazole (16865-11-5) → 1-benzyl-2,5,6-trichlorobenzimidazole (142372-26-7)

Guidance literature:

In methanol; chloroform; acetonitrile;

Reference yield:

4,5-Dichloro-1,2-phenylenediamine (5348-42-5) → 1-benzyl-2,5,6-trichlorobenzimidazole (142372-26-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 0.5 h / 150 °C

2: POCl₃, HCl / 3 h / 150 °C

3: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, 1 h

With hydrogenchloride; sodium hydride; trichlorophosphate;

DOI:10.1021/jm960442e

upstream raw materials:

benzyl bromide

2,5,6-trichloro-1H-benzo[d]imidazole

4,5-Dichloro-1,2-phenylenediamine

5,6-dichloro-1,3-dihydrobenzoimidazol-2-one