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Phenformin

Base Information Edit
  • Chemical Name:Phenformin
  • CAS No.:114-86-3
  • Molecular Formula:C10H15N5
  • Molecular Weight:205.263
  • Hs Code.:2925290090
  • European Community (EC) Number:204-057-4
  • UNII:DD5K7529CE
  • DSSTox Substance ID:DTXSID1023449
  • Nikkaji Number:J10.592I
  • Wikipedia:Phenformin
  • Wikidata:Q753100
  • NCI Thesaurus Code:C81700
  • Metabolomics Workbench ID:43182
  • ChEMBL ID:CHEMBL170988
  • Mol file:114-86-3.mol
Phenformin

Synonyms:Biguanide,1-phenethyl- (6CI,8CI);(Phenylethyl)biguanide;1-Phenethylbiguanide;Cronoformin;Debeone;Diabis;Dibiraf;Dibotin;Fenfoduron;Fenformin;Fenormin;Glukopostin;Glyphen;Phenethylbiguanide;

Suppliers and Price of Phenformin
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Phenformin
  • 250g
  • $ 382.00
  • TRC
  • N-Phenethylbiguanide
  • 100mg
  • $ 50.00
  • SynQuest Laboratories
  • N-Phenethylbiguanide
  • 5 g
  • $ 415.00
  • Crysdot
  • N-Phenethylbiguanide 95+%
  • 25g
  • $ 588.00
  • Apolloscientific
  • N-Phenethylbiguanide
  • 5g
  • $ 350.00
  • Alichem
  • N-Phenethylbiguanide
  • 25g
  • $ 599.76
  • AK Scientific
  • Phenformin
  • 1g
  • $ 154.00
Total 77 raw suppliers
Chemical Property of Phenformin Edit
Chemical Property:
  • Appearance/Colour:white powder 
  • Vapor Pressure:4.71E-07mmHg at 25°C 
  • Melting Point:280-282°C 
  • Refractive Index:1.62 
  • Boiling Point:413.7 °C at 760 mmHg 
  • PKA:pKa 3.1/12.9±0.01(H2O,t =25,I>0.1) (Uncertain) 
  • Flash Point:204 °C 
  • PSA:97.78000 
  • Density:1.24 g/cm3 
  • LogP:2.72010 
  • XLogP3:-0.8
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:1
  • Rotatable Bond Count:4
  • Exact Mass:205.13274550
  • Heavy Atom Count:15
  • Complexity:236
Purity/Quality:

99% , *data from raw suppliers

Phenformin *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn 
  • Hazard Codes:Xn 
  • Statements: 22 
  • Safety Statements: 36 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1=CC=C(C=C1)CCN=C(N)N=C(N)N
  • Recent ClinicalTrials:Clinical Trial of Phenformin in Combination With BRAF Inhibitor + MEK Inhibitor for Patients With BRAF-mutated Melanoma
  • Uses N-Phenethylbiguanide is used in cancer treatment methods using thermotherapy and/or enhanced immunotherapy.
  • Therapeutic Function Antidiabetic
Technology Process of Phenformin

There total 4 articles about Phenformin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With potassium hydroxide; In isopropyl alcohol; at 50 ℃; for 2h;
DOI:10.1016/j.bmc.2013.02.015

Reference yield:

Guidance literature:
Phenethylamin, 14C-Dicyandiamid;
DOI:10.1111/j.1432-1033.1972.tb01846.x
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