(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

Base Information

Chemical Name:(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol
CAS No.:1447721-11-0
Molecular Formula:C₃₇H₃₄N₂O₅
Molecular Weight:586.687
Hs Code.:

Synonyms:(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

Suppliers and Price of (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

There total 5 articles about (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1430339-86-8
(2R,3S,5R)-2-(hydroxymethyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 1447721-11-0
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

Guidance literature:: With pyridine; at 25 ℃; for 16h; Inert atmosphere;
DOI:10.1021/ja311434s

Reference yield:

: 1447720-48-0
((2R,3S,5R)-3-((4-methylbenzoyl)oxy)-5-(1H-perimidin-1-yl)tetrahydrofuran-2-yl)methyl 4-methylbenzoate

: 1447721-11-0
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium methylate / tetrahydrofuran; methanol / 2 h / 25 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: pyridine / 16 h / 25 °C / Inert atmosphere

With pyridine; sodium methylate; In tetrahydrofuran; methanol;
DOI:10.1021/ja311434s

Reference yield:

: 204-02-4
1-H-perimidine

: 1447721-11-0
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1H-perimidin-1-yl)tetrahydrofuran-3-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: sodium methylate / tetrahydrofuran; methanol / 2 h / 25 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: pyridine / 16 h / 25 °C / Inert atmosphere

With pyridine; sodium methylate; sodium hydride; In tetrahydrofuran; methanol;
DOI:10.1021/ja311434s