5-{[(Tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylic acid

Base Information

Chemical Name:5-{[(Tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylic acid
CAS No.:178446-63-4
Molecular Formula:C₁₃H₁₅NO₆
Molecular Weight:281.265
Hs Code.:
European Community (EC) Number:958-128-6

Synonyms:178446-63-4;5-{[(tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylic acid;5-[(2-methylpropan-2-yl)oxycarbonylamino]benzene-1,3-dicarboxylic acid;5-(tert-Butoxycarbonylamino)isophthalic acid;SCHEMBL2890076;SRUMAAHZHIHIQB-UHFFFAOYSA-N;AKOS010065292;5-(tert-butoxycarbonyl)aminoisophthalic acid;CS-0239665;t-Butyl N-[(3,5-dicarboxy)phenyl]carbamate;5-((t-butoxycarbonyl)amino)-isophthalic acid;EN300-217347;Z594114076;5-{[(tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylicacid

Suppliers and Price of 5-{[(Tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 5-{[(Tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylic acid

Chemical Property:

Vapor Pressure:1.6E-08mmHg at 25°C
XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:281.08993720
Heavy Atom Count:20
Complexity:378

Purity/Quality:: 99.3% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC(=CC(=C1)C(=O)O)C(=O)O

Technology Process of 5-{[(Tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylic acid

There total 2 articles about 5-{[(Tert-butoxy)carbonyl]amino}benzene-1,3-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 99-27-4
dimethyl 5-aminoisophthalate

: 178446-63-4
5-[(tert-butyloxycarbonyl)amino]-isophthalic acid

Guidance literature:: dimethyl 5-aminoisophthalate; With methanol; water; sodium hydroxide; at 20 ℃;

di-tert-butyl dicarbonate; In 1,4-dioxane; at 20 ℃;

Reference yield: 98.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 99-31-0
5-aminoisophthalic acid

: 178446-63-4
5-[(tert-butyloxycarbonyl)amino]-isophthalic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; at 0 - 20 ℃;
DOI:10.1021/ol016158l

Reference yield: 95.0%

: 2450-71-7
Propargylamine

: 178446-63-4
5-[(tert-butyloxycarbonyl)amino]-isophthalic acid

: 940005-72-1
(3,5-bis(prop-2-ynylcarbamoyl)phenyl)-carbamic acid tert-butyl ester

Guidance literature:: With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In tetrahydrofuran; for 48h;
DOI:10.1021/acs.bioconjchem.1c00115