4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

Base Information

Chemical Name:4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine
CAS No.:1347759-26-5
Molecular Formula:C₁₅H₁₃ClIN₃O
Molecular Weight:413.645
Hs Code.:

Synonyms:4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

Suppliers and Price of 4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

There total 6 articles about 4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1347759-25-4
4-chloro-3-iodo-6-methyl-1H-pyrazolo[4,3-c]pyridine

: 824-94-2
p-methoxybenzyl chloride

: 1347759-26-5
4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

Guidance literature:: With potassium hydroxide; In N,N-dimethyl-formamide; at 25 ℃;

Reference yield:

: 138642-40-7
methyl 2,4-dichloro-6-methylpyridine-3-carboxylate

: 1347759-26-5
4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: diisobutylaluminium hydride / dichloromethane; toluene / 2.5 h / -78 °C

1.2: -78 - 20 °C

2.1: triethylamine; oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 - 20 °C

3.1: hydrazine hydrate / 1,2-dimethoxyethane / 16 h / 80 °C

4.1: potassium hydroxide; iodine / 1,4-dioxane / 4 h / 70 °C

5.1: potassium hydroxide / N,N-dimethyl-formamide / 25 °C

With oxalyl dichloride; iodine; diisobutylaluminium hydride; hydrazine hydrate; dimethyl sulfoxide; triethylamine; potassium hydroxide; In 1,4-dioxane; 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide; toluene;

Reference yield:

: 374800-25-6
2,4-Dichloro-3-hydroxymethyl-6-methylpyridine

: 1347759-26-5
4-chloro-3-iodo-1-(4-methoxybenzyl)-6-methyl-1H-pyrazolo[4,3-c]pyridine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 - 20 °C

2: hydrazine hydrate / 1,2-dimethoxyethane / 16 h / 80 °C

3: potassium hydroxide; iodine / 1,4-dioxane / 4 h / 70 °C

4: potassium hydroxide / N,N-dimethyl-formamide / 25 °C

With oxalyl dichloride; iodine; hydrazine hydrate; dimethyl sulfoxide; triethylamine; potassium hydroxide; In 1,4-dioxane; 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide;