N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine

Base Information

• Chemical Name: N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine
• CAS No.: 217185-06-3
• Molecular Formula: C₂₅H₂₂N₄O₆
• Molecular Weight: 474.473
• Mol file: 217185-06-3.mol

Synonyms:N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine

Chemical Property of N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine

There total 1 articles about N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2,4-dimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine (40358-37-0,58414-04-3,119292-64-7) + 4-nitro-benzoyl chloride (122-04-3) → N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine (217185-06-3)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; at 8 - 10 ℃; for 5h;

DOI:10.1007/BF02645990

Reference yield: 72.0%

N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine (217185-06-3) → N,N'-di(p-aminobenzoyl)-2,4-dimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine (217185-07-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 18 - 20 ℃; for 5h; under 15200 - 16720 Torr;

DOI:10.1007/BF02645990

Reference yield: 70.0%

N,N'-di(p-nitrobenzoyl)-2,4-dimethyl-2,3,4,5-terahydro-1H-1,5-benzodiazepine (217185-06-3) → N,N'-di(p-aminobenzoyl)perhydro-1,4-diazepine

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 18 - 20 ℃; for 5h; under 15200 - 16720 Torr;

DOI:10.1007/BF02645990

upstream raw materials:

2,4-dimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine

4-nitro-benzoyl chloride

Downstream raw materials:

N,N'-di(p-aminobenzoyl)-2,4-dimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine