2-benzoyl-9H-fluoren-9-one

Base Information

• Chemical Name: 2-benzoyl-9H-fluoren-9-one
• CAS No.: 16275-68-6
• Molecular Formula: C20H12 O2
• Molecular Weight: 284.31
• Hs Code.: 2914399090
• Mol file: 16275-68-6.mol

Synonyms:Fluoren-9-one,2-benzoyl- (8CI); 2-Benzoylfluorenone

Chemical Property of 2-benzoyl-9H-fluoren-9-one

Chemical Property:

• Vapor Pressure: 4.02E-10mmHg at 25°C
• Boiling Point: 499.8°Cat760mmHg
• Flash Point: 184.8°C
• PSA: 34.14000
• Density: 1.275g/cm³
• LogP: 4.12900

Purity/Quality:

99%min ^*data from raw suppliers

2-BENZOYL-9H-FLUOREN-9-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-benzoyl-9H-fluoren-9-one

There total 5 articles about 2-benzoyl-9H-fluoren-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-benzoylfluorene (15860-31-8) → 2-benzoylfluorenone (16275-68-6)

Guidance literature:

With pyridine; potassium permanganate; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.9b03329

Reference yield: 61.0%

4'-benzoyl-[1,1'-biphenyl]-2-carbaldehyde (1433952-80-7) → 2-benzoylfluorenone (16275-68-6)

Guidance literature:

With dipotassium peroxodisulfate; tetraethylammonium bromide; In 1,2-dichloro-ethane; at 120 ℃; for 36h; Inert atmosphere;

DOI:10.1039/c2sc21823b

Reference yield:

9H-fluorene (86-73-7) → 2-benzoylfluorenone (16275-68-6)

Guidance literature:

Multi-step reaction with 2 steps

1: carbon disulfide; AlCl₃

2: sodium dichromate; glacial acetic acid

With carbon disulfide; aluminium trichloride; sodium dichromate; acetic acid;

upstream raw materials:

2-benzoylfluorene

acetic acid

9H-fluorene

benzyl chloride

Downstream raw materials:

potassium 2-benzoylfluorenone-7-sulfonate

2-benzoylfluorenone-7-sulfonic acid

Refernces

• 1、 Shi, Zhuangzhi,Glorius, Frank. "Synthesis of fluorenones via quaternary ammonium salt-promoted intramolecular dehydrogenative arylation of aldehydes". . p. 829 - 833. Retrieved 2013.