4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

Base Information

Chemical Name:4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride
CAS No.:152278-02-9
Molecular Formula:C₁₇H₁₇FN₂O₄S
Molecular Weight:364.397
Hs Code.:

Synonyms:4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

Suppliers and Price of 4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

There total 1 articles about 4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 102742-20-1
2-amino-4'-dimethylaminoacetophenone hydrochloride

: 402-55-1
4-fluorosulfonylbenzoyl chloride

: 152278-02-9
4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

Guidance literature:: With pyridine; In dichloromethane; for 12h; Ambient temperature;
DOI:10.1111/j.1751-1097.1997.tb03168.x

Reference yield: 92.0%

: 152278-02-9
4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

: 138219-56-4
4-(5-dimethylaminophenyl-2-oxazolyl)benzenesulfonyl fluoride

Guidance literature:: With sulfuric acid; for 24h;
DOI:10.1111/j.1751-1097.1997.tb03168.x

Reference yield:

: 152278-02-9
4-[2-(4-Dimethylamino-phenyl)-2-oxo-ethylcarbamoyl]-benzenesulfonyl fluoride

: 203250-34-4
3-{4-[5-(4-Dimethylamino-phenyl)-oxazol-2-yl]-benzenesulfonylamino}-propionic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / conc. H₂SO₄ / 24 h

2: 86 percent / 10percent aq. NaOH / 2 h / Heating

3: 81 percent / POCl₃ / 1 h / Heating

4: 93 percent / Et₃N / dimethylformamide / 12 h / Ambient temperature

5: 94 percent / 1 M aq. NaOH / methanol / 12 h / Ambient temperature

With sodium hydroxide; sulfuric acid; triethylamine; trichlorophosphate; In methanol; N,N-dimethyl-formamide;
DOI:10.1111/j.1751-1097.1997.tb03168.x