17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan

Base Information

Chemical Name:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan
CAS No.:1032280-59-3
Molecular Formula:C₂₈H₃₁NO₄
Molecular Weight:445.558
Hs Code.:

Synonyms:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan

Suppliers and Price of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan

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Technology Process of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan

There total 1 articles about 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 153567-11-4
2,2,2-trichloroethyl (4'R,7a'R,12b'S)-9'-(benzyloxy)-1',2',4',6'-tetrahydro-3'H,7a'Hspiro[[1,3]dioxolane-2,7'-[4,12]methanobenzofuro[3,2-e]isoquinoline]-3'-carboxylate

: 149-73-5
trimethyl orthoformate

: 1032280-59-3
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan

: 1032280-22-0
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,6-dimethoxymorphinan

Guidance literature:: 2,2,2-trichloroethyl (4'R,7a'R,12b'S)-9'-(benzyloxy)-1',2',4',6'-tetrahydro-3'H,7a'Hspiro[[1,3]dioxolane-2,7'-[4,12]methanobenzofuro[3,2-e]isoquinoline]-3'-carboxylate; trimethyl orthoformate; With sulfuric acid;

With ammonia; In water; Product distribution / selectivity;