3-Chloro-alpha-phenylbenzeneethanamine

Base Information

• Chemical Name: 3-Chloro-alpha-phenylbenzeneethanamine
• CAS No.: 74533-86-1
• Molecular Formula: C₁₄H₁₄ClN
• Molecular Weight: 231.725
• European Community (EC) Number: 616-112-3
• DSSTox Substance ID: DTXSID701295798
• Mol file: 74533-86-1.mol

Synonyms:SCHEMBL949577;DXUXYVHIIOWROF-UHFFFAOYSA-N;DTXSID701295798;3-Chloro-alpha-phenylbenzeneethanamine;2-(3-chlorophenyl)-1-phenyl-ethyl amine;74533-86-1

Chemical Property of 3-Chloro-alpha-phenylbenzeneethanamine

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 231.0814771
• Heavy Atom Count: 16
• Complexity: 201

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(CC2=CC(=CC=C2)Cl)N

Technology Process of 3-Chloro-alpha-phenylbenzeneethanamine

There total 3 articles about 3-Chloro-alpha-phenylbenzeneethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-benzeneacetyl chloride (41904-39-6) → 2-(3-chloro-phenyl)-1-phenyl-ethylamine (74533-86-1)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / CS₂

2: 4>2CO₃, HCO₂H

With aluminium trichloride; formic acid; ammonium carbonate; In carbon disulfide;

Reference yield:

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-(3-chloro-phenyl)-1-phenyl-ethylamine (74533-86-1)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / CS₂

2: 4>2CO₃, HCO₂H

With aluminium trichloride; formic acid; ammonium carbonate; In carbon disulfide;

Reference yield:

2-(3-chlorophenyl)-1-phenylethanone (27798-43-2) → 2-(3-chloro-phenyl)-1-phenyl-ethylamine (74533-86-1)

Guidance literature:

With formic acid; ammonium carbonate;

upstream raw materials:

2-(3-chlorophenyl)-1-phenylethanone

3-chloro-benzeneacetyl chloride

benzene

Downstream raw materials:

1-(2-(3-chlorophenyl)-1-phenyl-ethyl)-3-(2-chloro-propyl)-urea