gamma-Caprolactone

Base Information Edit

Chemical Name:gamma-Caprolactone
CAS No.:695-06-7
Deprecated CAS:57129-70-1
Molecular Formula:C6H10O2
Molecular Weight:114.144
Hs Code.:29322090
European Community (EC) Number:211-778-8
NSC Number:134769,24255
UNII:J16NAT1G41
DSSTox Substance ID:DTXSID8041298
Nikkaji Number:J45.665I
Wikidata:Q27158424
Metabolomics Workbench ID:4344
ChEMBL ID:CHEMBL192458
Mol file:695-06-7.mol

Synonyms:4-hexanolide

Suppliers and Price of gamma-Caprolactone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
γ-Caprolactone
5g
$ 75.00

TCI Chemical
gamma-Hexanolactone >98.0%(GC)
25mL
$ 30.00

Sigma-Aldrich
γ-Hexalactone natural,97%,FG
500 g
$ 2220.00

Sigma-Aldrich
γ-Hexalactone natural, 97%, FG
500g-k
$ 2220.00

Sigma-Aldrich
γ-Hexalactone ≥98%,FCC,FG
10 kg
$ 1390.00

Sigma-Aldrich
γ-Hexalactone ≥98%, FCC, FG
10kg-k
$ 1390.00

Sigma-Aldrich
γ-Hexalactone natural,97%,FG
1 SAMPLE-K
$ 60.00

Sigma-Aldrich
γ-Hexalactone analytical standard
1ml
$ 52.30

Sigma-Aldrich
γ-Hexalactone ≥98%,FCC,FG
1 SAMPLE-K
$ 50.00

Sigma-Aldrich
γ-Hexalactone natural, 97%, FG
sample-k
$ 50.00

Total 101 raw suppliers

Chemical Property of gamma-Caprolactone Edit

Chemical Property:

Appearance/Colour:colourless to pale yellow liquid with a herbaceous, sweet odour
Vapor Pressure:0.152mmHg at 25°C
Melting Point:-18 °C
Refractive Index:n20/D 1.439(lit.)
Boiling Point:214.904 °C at 760 mmHg
Flash Point:79.338 °C
PSA：26.30000
Density:1.003 g/cm³
LogP:1.10200
Storage Temp.:Store below +30°C.
Water Solubility.:77g/L at 20℃
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:114.068079557
Heavy Atom Count:8
Complexity:98.7

Purity/Quality:

99% ^*data from raw suppliers

γ-Caprolactone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-36
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Classes -> Lactones
Canonical SMILES:CCC1CCC(=O)O1
Description gamma-Hexalactone has a warm, powerful, herbaceous, sweet odor and a sweet, coumarin-caramel taste. May be prepared by reduction of sorbic acid using Zn, Sn, or SnCl2 and concentrated HCL in acetic acid solution at 85°C; from ethylene oxide and sodio-malonic ester; also from propyl alcohol and methylacrylate in the presence of di-tert-butyl peroxide.
Uses 4-Hexanolide was used as curing agent for diglycidyl ether of bisphenol A with ytterbium triflate as an initiator. γ-Hexalactone may be used as an analytical standard for the determination of the analyte in wine, fruits, biological samples, meat products, and e-cigarette refill solutions by various chromatography techniques. γ-Caprolactone was used as curing agent for diglycidyl ether of bisphenol A with ytterbium triflate as an initiator.

Technology Process of gamma-Caprolactone

There total 79 articles about gamma-Caprolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 2407-43-4
5-ethyl-5H-furan-2-one

: 695-06-7
hexan-4-olide

Guidance literature:: With dodecacarbonyltetrarhodium⁽⁰⁾; triphenylphosphine; isopropyl alcohol; at 220 ℃; for 1h;
DOI:10.1016/0022-328X(91)86063-V

Reference yield: 88.0%

: 4219-24-3
hex-3-enoic acid

: 695-06-7
hexan-4-olide

Guidance literature:: With calcium(II) bis(trifluoromethanesulfonyl)imide; tert-butylammonium hexafluorophosphate(V); at 80 ℃; for 2h; Sealed tube;
DOI:10.1021/acs.orglett.9b02705

Reference yield: 86.0%

: 823-22-3,26991-67-3
5-hexanolide

: 695-06-7
hexan-4-olide

Guidance literature:: With W(OTf)₆; at 180 ℃; for 10h; Schlenk technique; Ionic liquid; Inert atmosphere; Green chemistry;
DOI:10.1002/cssc.201800587