2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile

Base Information

Chemical Name:2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile
CAS No.:849402-28-4
Molecular Formula:C₁₇H₂₂F₃NO₃
Molecular Weight:345.362
Hs Code.:

Synonyms:2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile

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Chemical Property of 2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile

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Technology Process of 2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile

There total 2 articles about 2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 849402-27-3
1-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-2,2,2-trifluoroethanone

: 7677-24-9
trimethylsilyl cyanide

: 849402-28-4
2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile

Guidance literature:: 1-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-2,2,2-trifluoroethanone; trimethylsilyl cyanide; With potassium cyanide; 18-crown-6 ether; In dichloromethane; at 20 ℃;

With hydrogenchloride; water; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2008.11.069

Reference yield: 93.0%

: 849402-27-3
1-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-2,2,2-trifluoroethanone

: 7677-24-9
trimethylsilyl cyanide

: 151-50-8
potassium cyanide

: 849402-28-4
2-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-3,3,3-trifluoro-2-hydroxypropanenitrile

Guidance literature:: 1-(3,5-diisopropyl-4-(methoxymethoxy)phenyl)-2,2,2-trifluoroethanone; trimethylsilyl cyanide; potassium cyanide; 18-crown-6 ether; In dichloromethane;

With hydrogenchloride; In tetrahydrofuran; dichloromethane; water;