4'-Methyl-4-(p-tolyl)butyrophenone

Base Information

Chemical Name:4'-Methyl-4-(p-tolyl)butyrophenone
CAS No.:71607-33-5
Molecular Formula:C₁₈H₂₀O
Molecular Weight:252.356
Hs Code.:
European Community (EC) Number:275-673-9
DSSTox Substance ID:DTXSID30992161
Nikkaji Number:J289.231F
Wikidata:Q82982201
Mol file:71607-33-5.mol

Synonyms:4'-Methyl-4-(p-tolyl)butyrophenone;71607-33-5;1,4-bis(4-methylphenyl)butan-1-one;EINECS 275-673-9;DTXSID30992161;1,4-Bis(4-methylphenyl)-1-butanone

Suppliers and Price of 4'-Methyl-4-(p-tolyl)butyrophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4'-Methyl-4-(p-tolyl)butyrophenone

Chemical Property:

PSA：17.07000
LogP:4.50900
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:252.151415257
Heavy Atom Count:19
Complexity:267

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CCCC(=O)C2=CC=C(C=C2)C

Technology Process of 4'-Methyl-4-(p-tolyl)butyrophenone

There total 2 articles about 4'-Methyl-4-(p-tolyl)butyrophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 29480-08-8
1-(4-methylphenyl)cyclobutan-1-ol

: 29540-83-8
p-tolyl triflate

: 71607-33-5
1,4-di-p-tolylbutan-1-one

Guidance literature:: With bis(triphenylphosphine)nickel(II) chloride; sodium t-butanolate; In toluene; at 90 ℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.0c02209

Reference yield:

: 106-44-5
p-cresol

: 71607-33-5
1,4-di-p-tolylbutan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere; Schlenk technique; Sealed tube

2: bis(triphenylphosphine)nickel(II) chloride; sodium t-butanolate / toluene / 12 h / 90 °C / Schlenk technique; Inert atmosphere; Sealed tube

With pyridine; bis(triphenylphosphine)nickel(II) chloride; sodium t-butanolate; In dichloromethane; toluene;
DOI:10.1021/acs.joc.0c02209