C₁₅H₁₂BrFO₃

Base Information

• Chemical Name: C₁₅H₁₂BrFO₃
• CAS No.: 1187189-72-5
• Molecular Formula: C₁₅H₁₂BrFO₃
• Molecular Weight: 339.161
• Mol file: 1187189-72-5.mol

Synonyms:C₁₅H₁₂BrFO₃

Chemical Property of C₁₅H₁₂BrFO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₂BrFO₃

There total 6 articles about C₁₅H₁₂BrFO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C13H9Br2FO (1187189-71-4) + sodium acetate (127-09-3) → C15H12BrFO3 (1187189-72-5)

Guidance literature:

In N,N-dimethyl-formamide; at 70 ℃; for 5h;

Reference yield:

5-Fluoro-2-nitrotoluene (446-33-3) → C15H12BrFO3 (1187189-72-5)

Guidance literature:

Multi-step reaction with 5 steps

1: potassium carbonate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere

2: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

3: tert.-butylnitrite; copper(ll) bromide / acetonitrile / -10 °C

4: dibenzoyl peroxide; N-Bromosuccinimide / tetrachloromethane / 70 °C

5: N,N-dimethyl-formamide / 5 h / 70 °C

With N-Bromosuccinimide; tert.-butylnitrite; palladium on activated charcoal; hydrogen; potassium carbonate; copper(ll) bromide; dibenzoyl peroxide; In tetrachloromethane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

4-Fluorophenol (371-41-5) → C15H12BrFO3 (1187189-72-5)

Guidance literature:

Multi-step reaction with 5 steps

1: potassium carbonate / N,N-dimethyl-formamide / 80 °C / Inert atmosphere

2: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

3: tert.-butylnitrite; copper(ll) bromide / acetonitrile / -10 °C

4: dibenzoyl peroxide; N-Bromosuccinimide / tetrachloromethane / 70 °C

5: N,N-dimethyl-formamide / 5 h / 70 °C

With N-Bromosuccinimide; tert.-butylnitrite; palladium on activated charcoal; hydrogen; potassium carbonate; copper(ll) bromide; dibenzoyl peroxide; In tetrachloromethane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;

upstream raw materials:

C₁₃H₉Br₂FO

sodium acetate

5-Fluoro-2-nitrotoluene

4-Fluorophenol

Downstream raw materials:

5-(4-fluorophenoxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

C₁₃H₁₀BrFO₂