Technology Process of methylthiocarbamic acid O-[4-(2-carbazol-9-ylethoxy)phenyl]ester
There total 6 articles about methylthiocarbamic acid O-[4-(2-carbazol-9-ylethoxy)phenyl]ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methanol;
With
sodium hydride;
In
mineral oil;
at 20 ℃;
for 1h;
Inert atmosphere;
9-[2-(4-isothiocyanatophenoxy)ethyl]-9H-carbazole;
In
mineral oil;
at 20 ℃;
for 5h;
DOI:10.1016/j.bmcl.2012.03.010
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere
1.2: 24 h / 70 °C / Inert atmosphere
2.1: triethylamine / N,N-dimethyl-formamide / 4 h / 20 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 24 h / 70 °C
4.1: palladium 10% on activated carbon; hydrogen / methanol; N,N-dimethyl-formamide / 4 h / 20 °C / 760.05 Torr
5.1: potassium carbonate / chloroform / 0.5 h / 20 °C
5.2: 4 h / 20 °C
6.1: sodium hydride / mineral oil / 1 h / 20 °C / Inert atmosphere
6.2: 5 h / 20 °C
With
palladium 10% on activated carbon; hydrogen; sodium hydride; potassium carbonate; triethylamine;
In
methanol; chloroform; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.bmcl.2012.03.010
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: palladium 10% on activated carbon; hydrogen / methanol; N,N-dimethyl-formamide / 4 h / 20 °C / 760.05 Torr
2.1: potassium carbonate / chloroform / 0.5 h / 20 °C
2.2: 4 h / 20 °C
3.1: sodium hydride / mineral oil / 1 h / 20 °C / Inert atmosphere
3.2: 5 h / 20 °C
With
palladium 10% on activated carbon; hydrogen; sodium hydride; potassium carbonate;
In
methanol; chloroform; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.bmcl.2012.03.010
