2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one

Base Information

• Chemical Name: 2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one
• CAS No.: 856633-77-7
• Molecular Formula: C₁₆H₁₂N₂O₆S
• Molecular Weight: 360.347
• Mol file: 856633-77-7.mol

Synonyms:2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one

Chemical Property of 2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one

There total 2 articles about 2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-acetylnitrobenzene (577-59-3) + dimethyl sulfoxide (67-68-5,8070-53-9) + saccharin (81-07-2) → 2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ6-benz[d]isothiazol-3-one (856633-77-7)

Guidance literature:

With ruthenium trichloride; 1,10-Phenanthroline; sodium carbonate; Selectfluor; at 120 ℃; for 10h;

DOI:10.1039/c4ra14249g

Reference yield:

3-(dimethylamino)-1-(2-nitrophenyl)propan-1-one (176859-85-1) + saccharin (81-07-2) → 2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ6-benz[d]isothiazol-3-one (856633-77-7)

Guidance literature:

With sodium ethanolate;

Reference yield:

2-[3-(2-nitro-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ6-benz[d]isothiazol-3-one (856633-77-7) → 2-[3-(2-amino-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ6-benz[d]isothiazol-3-one (131620-12-7)

Guidance literature:

With hydrogenchloride; acetic acid; tin(ll) chloride;

upstream raw materials:

3-(dimethylamino)-1-(2-nitrophenyl)propan-1-one

saccharin

2-acetylnitrobenzene

dimethyl sulfoxide

Downstream raw materials:

2-[3-(2-amino-phenyl)-3-oxo-propyl]-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one

kynuramine