LEAD ACETATE

Base Information

• Chemical Name: LEAD ACETATE
• CAS No.: 301-04-2
• Molecular Formula: C2H4O2.1/2Pb
• Molecular Weight: 325.289
• Hs Code.: 3822001000
• Mol file: 301-04-2.mol

Synonyms:Acetate de plomb;Acetic acid lead(2+) salt;Acetic acid, lead salt;Bleiacetat;CCRIS 356;Caswell No. 523A;Dibasic lead acetate;HSDB 1404;Lead acetate (Pb(Ac)2);Normal lead acetate;Plumbous acetate;Salt of saturn;

Chemical Property of LEAD ACETATE

Chemical Property:

• Vapor Pressure: 15.7hPa at 25℃
• Melting Point: 75 °C (dec.)(lit.)
• Boiling Point: 117.1oC at 760 mmHg
• Flash Point: 40oC
• PSA: 37.30000
• Density: 1.068g/cm3
• LogP: -0.06490
• Storage Temp.: 2-8°C
• Water Solubility.: g/100g H2O: 19.7 (0°C), 55.2 (25°C); equilibrium solid phase, Pb(CH3COO)2 ·3H2O [KRU93]; g/100mL H2O: 44.3 (20°C), 221 (50°C) [KIR78]

Purity/Quality:

Lead Diacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T, N
• Hazard Codes: T,N
• Statements: 61-33-48/22-50/53-62
• Safety Statements: 53-45-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Physical Properties: Lead(II) acetate, Pb(CH3COO)2, is a white crystalline material with a sweet taste and is also classified by one of the following trivial names: lead sugar, Saturn salt and Goulard powder, respectively. Lead acetate is water and glycerin soluble, and is toxic (like most lead compounds).The anhydrous salt is a white crystalline solid; very sweet taste; density 3.25 g/cm3 at 20°C; melts at 280°C; very soluble in cold water (44.39g/100g at 20°C); solubility is much greater in hot water (221g/100g at 50°C; also soluble in alcohols.The trihydrate is a colorless monoclinic crystal or white granule or powder; refractive index 1.567 (along the beta axis); faint vinegar odor; intense sweet taste and then metallic after-taste; slowly effloresces; density 2.55 g/cm3; melts at 75°C upon rapid heating; loses some of its water of crystallization on heating which dissolves in it; decomposes at 200°C; highly soluble in water (45.61g/100g at 15°C and 200g/100g at 100°C); insoluble in alcohol.The decahydrate is white rhombic crystal; density 1.69 g/cm3; melts at 22°C; soluble in water but insoluble in alcohol.
• Uses: Lead (II) acetate, as well as white lead, have been used in cosmetics throughout history, though this practice has ceased in Western countries . It is still used in men's hair coloring products like Grecian Formula.Lead acetate is used as a reagent to make other lead compounds and as a fixative for some dyes. In low concentrations, it is the principal active ingredient in progressive types of hair colouring dyes. These products are applied over a period of time to achieve a gradual coloring effect. Lead (Il) acetate is also used as a mordant in textile printing anddyeing,and as a drier in paints and varnishes.Lead (II) acetate paper is used to detect the poisonous gas hydrogen sulfide. The gas reacts with lead (II) acetate on the moistened test paper to form a grey precipitate of lead (II) sulfide.Lead (II) acetate solution was a commonly used folk remedy for sore nipples . In modern medicine, for a time, it was used as an astringent, in the form of Goulard's Extract.An aqueous solution of lead (II) acetate is the by product of the 50 / 50 mixture of hydrogen peroxide and white vinegar used in the cleaning and maintenance of stainless steel fire arm suppressors (silencers) and compensators. The solution is agitated by the bubbling action of the hydrogen peroxide, and the main reaction is the dissolution of lead deposits within the suppressor by the acetic acid, which forms lead acetate.https://www.chemeurope.com/https://pubchem.ncbi.nlm.nih.govMasterly's Series LAB MANUAL OF PHARMACEUTICS-I For Diploma Pharmacy First Mordant in cotton dyes; lead coating for metals; drier in paints, varnishes and pigment inks; colorant in hair dyes. Weighting silks; manufacture of lead salts, chrome-yellow; as analytical reagent for detection of sulfide, determination of CrO3, MoO3. 2 – 1 - Sweetener Like other lead (II) salts, lead (II) acetate has a sweet taste, which has led to its use as a sugar substitute throughout history. The ancient Romans, who had few sweeteners besides honey, would boil must (grape juice) in lead pots to produce a reduced sugar syrup called defrutum, concentrated again into sapa. This syrup was used to sweeten wine and to sweeten and preserve fruit. It is possible that lead(II) acetate or other lead compounds leaching into the syrup might have caused lead poisoning in anyone consuming it . Lead acetate is no longer used in the production of sweeteners in most of the world because of its recognized toxicity. Modern chemistry can easily detect it, which has all but stopped the illegal use that continued decades after legal use as a sweetener was banned . 2 – 1 - Sweetener2 – 1 – 1 - Resultant deaths Pope Clement II died in October 1047. A toxicologic examination of his remains conducted in the mid – 20 th century confirmed centuries-old rumors that he had been poisoned with lead sugar.It is not clear if he was assassinated. In 1787 painter Albert Christoph Dies swallowed, by accident, approximately 21 g of lead acetate. His recovery from this poison was slow and incomplete. He lived with illnesses until his death in 1822 . Although the use of lead (II) acetate as a sweetener was already illegal at that time, composer Ludwig van Beethoven may have died of lead poisoning caused by wines adulterated with lead acetate. Mary Seacole applied lead (II) acetate, among other remedies, against an epidemic of cholera in Panama.
• Description: Lead acetate is stable under ordinary conditions of use and storage. Lead acetate is incompatible with bromates, phenol, chloral hydrate, sulphides, hydrogen peroxide, resorcinol, salicylic acid, sulphites, vegetable infusions, alkalis, tannin, phosphates, citrates, chlorides, carbonates, tartrates, and acids. Lead (II) acetate, as well as white lead, has been used in cosmetics throughout history, though this practice has ceased in Western countries. It is still used in men’s hair colouring. Lead (II) acetate paper is used to detect the poisonous gas hydrogen sulphide. The gas reacts with lead (II) acetate on the moistened test paper to form a grey precipitate of lead (II) sulphide.

Technology Process of LEAD ACETATE

There total 81 articles about LEAD ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

vanadocene + lead(IV) tetraacetate (546-67-8) → {(η5-cyclopentadienyl)vanadium diacetate}2 + lead acetate (301-04-2) + cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8)

Guidance literature:

In toluene; molar ratio Cp2V/Pb-compound 1/1, sealed ampoule, 20°C, 48 h;

Reference yield: 86.0%

lead(IV) tetraacetate (546-67-8) + Tributyl-((E)-3-phenyl-allyloxymethyl)-stannane (121508-11-0) → lead acetate (301-04-2) + Acetic acid (E)-3-phenyl-allyloxymethyl ester (121508-08-5) + tributyltin acetate (56-36-0)

Guidance literature:

With amonnium chloride; In dichloromethane; mixt. of organotin compd. and LTA in dry CH2Cl2 stirred at room temp. under N2 for 40 h, quenching with saturated ammonium chloride soln.; aqueous phase removed, extd. with chloroform, combd. organic phase dried, concd., silica gel column chromy. (hexane-chloroform 1:1); elem. anal., IR, NMR, MS;

DOI:10.1246/cl.1989.221

Reference yield: 79.0%

lead(IV) tetraacetate (546-67-8) + Tributyl-((E)-3,7-dimethyl-octa-2,6-dienyloxymethyl)-stannane (121508-14-3) → lead acetate (301-04-2) + Acetic acid (E)-3,7-dimethyl-octa-2,6-dienyloxymethyl ester (121508-10-9) + tributyltin acetate (56-36-0)

Guidance literature:

In dichloromethane; mixt. of organotin compd. and LTA in dry CH2Cl2 stirred at room temp. under N2 for 40 h; quenching with saturated ammonium chloride soln., aq. phase is removed, extd. with chloroform, combd. organic phases are dried, concd., silica gel column chromy. (hexane-chloroform), IR, NMR, MS;

DOI:10.1246/cl.1989.221

upstream raw materials:

lead(IV) tetraacetate

1-(Trimethylsilyloxy)cyclohexene

6-methyl-1-trimethylsiloxycyclohex-1-ene

camphor trimethylsilyl enol ether

Downstream raw materials:

lead(IV) tetraacetate

4-nitro-benzoic acid

Methyl 3-aminobenzoate

m-Toluic acid

Refernces

• 1、 Spiccia,West,Zhang. "Studies on the synthesis of Pb-Ti-oxo-alkoxo-carboxylato complexes". . p. 1851 - 1861. Retrieved 1998.
• 2、 Denham, H. G.. "". . p. 109 - 111. Retrieved 1919.
• 3、 Buston, Jonathan E. H.,Claridge, Tim D. W.,Heyes, Stephen J.,Leech, Michael A.,Moloney, Mark G.,Prout, Keith,Stevenson, Maya. "Structural investigations of a lead(IV) tetraacetate-pyridine complex". . p. 3195 - 3203. Retrieved 2005.
• 4、 Akhbari, Kamran,Morsali, Ali. "Solid- and solution-state structural transformations in flexible lead(ii) supramolecular polymers". . p. 8915 - 8918. Retrieved 2013/11/19.
• 5、 Sharma, Malti,Bhagi, Ajay K.,Sharma, Harish K.,Priti, Ritu Kansal,Kumar, Ram,Kapoor, Pramesh N.. "Precursors for mixed metal oxide nanoparticles: Synthesis and characterization of μ-oxoalkoxides of some bivalent metals and their β-diketonates". . p. 256 - 260. Retrieved 2007/10/03.