2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine

Base Information

• Chemical Name: 2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine
• CAS No.: 184637-53-4
• Molecular Formula: C₁₅H₂₀Cl₂N₂O
• Molecular Weight: 315.243
• Mol file: 184637-53-4.mol

Synonyms:2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine

Chemical Property of 2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine

There total 1 articles about 2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-ethyl-2-pyrrolidinemethanamine (26116-12-1) + 3,4-dichlorophenyl acetic acid (5807-30-7) → 2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine (184637-53-4)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; for 0.166667h; Ambient temperature;

DOI:10.1021/jm00101a011

Reference yield:

2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine (184637-53-4) → 2-<amino>methyl>-1-ethylpyrrolidine (144243-16-3)

Guidance literature:

With aluminium hydride; In tetrahydrofuran; for 0.333333h; Ambient temperature;

DOI:10.1021/jm00101a011

Reference yield:

2-<<(3,4-dichlorophenyl)acetamido>methyl>-1-ethylpyrrolidine (184637-53-4) → 2-<N-methylamino>methyl>-1-ethylpyrrolidine (144243-18-5)

Guidance literature:

Multi-step reaction with 3 steps

1: AlH₃ / tetrahydrofuran / 0.33 h / Ambient temperature

2: 100 percent / HCOOH / Heating

3: AlH₃ / tetrahydrofuran / 0.33 h / Ambient temperature

With aluminium hydride; formic acid; In tetrahydrofuran;

DOI:10.1021/jm00101a011

upstream raw materials:

1-ethyl-2-pyrrolidinemethanamine

3,4-dichlorophenyl acetic acid

Downstream raw materials:

2-<amino>methyl>-1-ethylpyrrolidine

2-<formamido>methyl>-1-ethylpyrrolidine

2-<N-methylamino>methyl>-1-ethylpyrrolidine