4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Base Information

Chemical Name:4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride
CAS No.:1978-61-6
Molecular Formula:C11H12 F N . Cl H
Molecular Weight:213.682
Hs Code.:29333999
European Community (EC) Number:217-836-9
NSC Number:89742
DSSTox Substance ID:DTXSID50173475
Mol file:1978-61-6.mol

Synonyms:4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride;1978-61-6;NSC 89742;EINECS 217-836-9;4-(p-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride;Pyridine, 4-(4-fluorophenyl)-1,2,3,6-tetrahydro-, hydrochloride;Pyridine, 1,2,3,6-tetrahydro-4-(p-fluorophenyl)-, hydrochloride;4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine;hydrochloride;4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride;4-(4-fluorophenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride;C11H12FN.ClH;SCHEMBL730625;C11-H12-F-N.Cl-H;DTXSID50173475;NSC89742;MFCD00035278;NSC-89742;AKOS015958960;TS-03052;LS-132022;Pyridine,2,3,6-tetrahydro-, hydrochloride;CS-0129010;FT-0616629;EN300-15327;C80045;J-513509;4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine HCl;4-(p-Fluorophenyl)-1,3,6-tetrahydropyridine hydrochloride;4-(4-fluoro-phenyl)-1,2,3,6-tetrahydro-pyridine hydrochloride;4-(4-fluoro-phenyl)-1,2,3,6-tetrahydropyridine hydrochloride;4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine,hydrochloride;Pyridine,2,3,6-tetrahydro-4-(p-fluorophenyl)-, hydrochloride

Suppliers and Price of 4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridineHydrochloride
500mg
$ 165.00

TRC
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridineHydrochloride
500mg
$ 200.00

TRC
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridineHydrochloride
50mg
$ 45.00

SynQuest Laboratories
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride
1 g
$ 232.00

Matrix Scientific
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride 95%
1g
$ 304.00

Crysdot
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride 95+%
1g
$ 185.00

ChemScene
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride ≥97.0%
1g
$ 55.00

Chemenu
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride 95%
5g
$ 533.00

Atlantic Research Chemicals
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride 95%
250mgs:
$ 49.48

Apolloscientific
4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridinehydrochloride
1g
$ 145.00

Total 23 raw suppliers

Chemical Property of 4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Chemical Property:

Vapor Pressure:0.00997mmHg at 25°C
Melting Point:169-173 °C
Boiling Point:264ºC at 760 mmHg
Flash Point:113.4ºC
PSA：12.03000
LogP:3.33320
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Water (Slightly)
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:213.0720553
Heavy Atom Count:14
Complexity:192

Purity/Quality:

99%, ^*data from raw suppliers

4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 40-23/24/25
Safety Statements: 45-38-36/37/39-28A

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC=C1C2=CC=C(C=C2)F.Cl
Uses A reagent in the preparation of 4-phenyl-tetrahydrophenyl substituted oxazolidinone derivatives with potent central nervous depressant, analgetic, and antiinflammatory activities as well as α1A adrene rgic receptor antagonists. A reagent in the preparation of 4-phenyl-tetrahydrophenyl substituted oxazolidinone derivatives with potent central nervous depressant, analgetic, and antiinflammatory activities as well as α1A adrenergic receptor antagonists.

Technology Process of 4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

There total 5 articles about 4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 460-00-4
1-Bromo-4-fluorobenzene

: 1978-61-6
4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: Mg / tetrahydrofuran

2: 1.) H₂, 2.) 50percent HCl / 1.) Pd/C / 1.) H₂O, 2.) H₂O, reflux

With hydrogenchloride; hydrogen; magnesium; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1021/jm00100a006

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 1978-61-6
4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: Mg / tetrahydrofuran

2: 1.) H₂, 2.) 50percent HCl / 1.) Pd/C / 1.) H₂O, 2.) H₂O, reflux

With hydrogenchloride; hydrogen; magnesium; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1021/jm00100a006

Reference yield:

: 163631-02-5
1-benzyl-4-(4-fluorophenyl)-4-hydroxypiperidine

: 1978-61-6
4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; Multistep reaction; 1.) H₂O, 2.) H₂O, reflux;
DOI:10.1021/jm00100a006