indol-3-yl 2-nitrophenyl sulphide

Base Information

• Chemical Name: indol-3-yl 2-nitrophenyl sulphide
• CAS No.: 72496-78-7
• Molecular Formula: C₁₄H₁₀N₂O₂S
• Molecular Weight: 270.312
• Mol file: 72496-78-7.mol

Synonyms:indol-3-yl 2-nitrophenyl sulphide

Chemical Property of indol-3-yl 2-nitrophenyl sulphide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of indol-3-yl 2-nitrophenyl sulphide

There total 11 articles about indol-3-yl 2-nitrophenyl sulphide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

indole (120-72-9) + 2-Nitrobenzenesulfonyl chloride (1694-92-4) → indol-3-yl 2-nitrophenyl sulphide (72496-78-7)

Guidance literature:

With 1,2,2,3,4,4-hexamethylphosphetane 1-oxide; phenylsilane; In 1,4-dioxane; at 40 ℃; Schlenk technique; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.201813919

Reference yield: 97.0%

indole (120-72-9) + 2-nitrobenzenesulfenyl chloride (7669-54-7) → indol-3-yl 2-nitrophenyl sulphide (72496-78-7)

Guidance literature:

With pyridine; In diethyl ether; at 25 ℃; for 0.333333h;

Reference yield: 90.0%

bis(2-nitrophenyl)disulfide (1155-00-6) + indole (120-72-9) → indol-3-yl 2-nitrophenyl sulphide (72496-78-7)

Guidance literature:

bis(2-nitrophenyl)disulfide; With tetrabutylammomium bromide; triethylamine; In dichloromethane; for 1h; Cooling with ice; Green chemistry;

indole; In dichloromethane; at 70 ℃; for 3.5h; Green chemistry;

DOI:10.1016/j.tetlet.2015.05.062

upstream raw materials:

indole

2-nitrobenzenesulfenyl chloride

bis(2-nitrophenyl)disulfide

1-(benzylsulfanyl)-2-nitrobenzene

Downstream raw materials:

indol-3-yl o-aminophenyl sulphide

3’H-spiro[indole-3,2’-[1,3]]benzothiazole-2(1H)-one