3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

Base Information

Chemical Name:3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester
CAS No.:1027978-68-2
Molecular Formula:C₆₅H₅₅NO₁₂S
Molecular Weight:1074.22
Hs Code.:

Synonyms:3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

Suppliers and Price of 3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

There total 8 articles about 3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 103-16-2
4-Benzyloxyphenol

: 1027978-68-2
3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Ph₃P, diethyl azodicarboxylate, 2.) t-BuOK / 1.) THF, a) RT, 4 h, b) reflux, 16 h, 2.) THF, RT, 24 h

2: tetrabutylammonium fluoride / tetrahydrofuran / 3 h / Ambient temperature

3: Et₃N, DMAP / CH₂Cl₂

With dmap; potassium tert-butylate; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm960581w

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 1027978-68-2
3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 63 percent / N,N-diisopropylethylamine / tetrahydrofuran / 21.5 h / 0 - 20 °C

2: 99 percent / imidazole / dimethylformamide / 16 h / Ambient temperature

3: 100 percent / LiBH₄ / tetrahydrofuran / 18 h

4: 1.) Ph₃P, diethyl azodicarboxylate, 2.) t-BuOK / 1.) THF, a) RT, 4 h, b) reflux, 16 h, 2.) THF, RT, 24 h

5: tetrabutylammonium fluoride / tetrahydrofuran / 3 h / Ambient temperature

6: Et₃N, DMAP / CH₂Cl₂

With 1H-imidazole; dmap; lithium borohydride; potassium tert-butylate; tetrabutyl ammonium fluoride; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm960581w

Reference yield:

: 158585-06-9
4-(6-Benzyloxy-2-(benzyloxycarbonyl)benzoyl)-3,5-dibenzyloxybenzoic Acid

: 1027978-68-2
3,5-Bis-benzyloxy-4-(2-benzyloxy-6-benzyloxycarbonyl-benzoyl)-benzoic acid 2-benzenesulfonylamino-3-(4-benzyloxy-phenoxy)-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride / CH₂Cl₂; dimethylformamide / 2 h / Ambient temperature

2: Et₃N, DMAP / CH₂Cl₂

With dmap; oxalyl dichloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm960581w