3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

Base Information

Chemical Name:3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride
CAS No.:141899-22-1
Molecular Formula:C₁₆H₂₀FNO₂*ClH
Molecular Weight:313.8
Hs Code.:

Synonyms:3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

Suppliers and Price of 3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

Chemical Property:

Purity/Quality:: 99%+, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

There total 4 articles about 3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: anhydroecgonine methyl ester hydrochloride

: 352-13-6
4-flourophenylmagnesium bromide

: 141899-22-1
3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

Guidance literature:: In diethyl ether; at -70 ℃; Temperature; Inert atmosphere;

Reference yield:

: 481-37-8
ecgonine

: 141899-22-1
3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: trichlorophosphate / 1 h / Reflux

2: -73 °C

3: diethyl ether / -70 °C / Inert atmosphere

With trichlorophosphate; In diethyl ether; 3: |Michael Addition;

Reference yield:

: (-)-cocaine.HCl

: 141899-22-1
3β-(4'-fluorophenyl)tropan-2β-carboxylic acid methyl ester hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride / water / 72 h / 20 °C / Reflux

2: trichlorophosphate / 1 h / Reflux

3: -73 °C

4: diethyl ether / -70 °C / Inert atmosphere

With hydrogenchloride; trichlorophosphate; In diethyl ether; water; 4: |Michael Addition;