C₇₅H₈₈N₁₀O₁₄

Base Information

• Chemical Name: C₇₅H₈₈N₁₀O₁₄
• CAS No.: 174007-70-6
• Molecular Formula: C₇₅H₈₈N₁₀O₁₄
• Molecular Weight: 1353.58
• Mol file: 174007-70-6.mol

Synonyms:C₇₅H₈₈N₁₀O₁₄

Chemical Property of C₇₅H₈₈N₁₀O₁₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₅H₈₈N₁₀O₁₄

There total 16 articles about C₇₅H₈₈N₁₀O₁₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-hydroxypentylamine (2508-29-4) → C75H88N10O14 (174007-70-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 85 percent / CH₂Cl₂ / 16 h / 20 °C

2: 100 percent / hydrogen / 10 percent Pd/C / methanol / 16 h / 15 °C / 760 Torr

3: 96 percent / Et₃N / dimethylformamide / 16 h / 20 °C

4: 1.) DMSO, oxalyl chloride / 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂/DMSO, -78 deg C

5: 48 percent / glacial HOAc, NaCNBH₃ / methanol / 2 h / 20 °C

With oxalyl dichloride; hydrogen; sodium cyanoborohydride; acetic acid; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(95)01994-S

Reference yield:

[(S)-2-Carbamoyl-1-(5-hydroxy-pentylcarbamoyl)-ethyl]-carbamic acid benzyl ester (174007-66-0) → C75H88N10O14 (174007-70-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 100 percent / hydrogen / 10 percent Pd/C / methanol / 16 h / 15 °C / 760 Torr

2: 96 percent / Et₃N / dimethylformamide / 16 h / 20 °C

3: 1.) DMSO, oxalyl chloride / 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂/DMSO, -78 deg C

4: 48 percent / glacial HOAc, NaCNBH₃ / methanol / 2 h / 20 °C

With oxalyl dichloride; hydrogen; sodium cyanoborohydride; acetic acid; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(95)01994-S

Reference yield:

bis(3-aminopropyl)amine (56-18-8) → C75H88N10O14 (174007-70-6)

Guidance literature:

Multi-step reaction with 5 steps

1: mono-BOC protection

2: 88 percent / DCC, HOBt / CH₂Cl₂ / 16 h / 20 °C

3: 96 percent / 2 M NaOH / 16 h / 20 °C

4: 95 percent / TFA / CH₂Cl₂ / 0.5 h / 0 °C

5: 48 percent / glacial HOAc, NaCNBH₃ / methanol / 2 h / 20 °C

With sodium hydroxide; sodium cyanoborohydride; benzotriazol-1-ol; acetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; In methanol; dichloromethane;

DOI:10.1016/0040-4039(95)01994-S

upstream raw materials:

bis(3-aminopropyl)amine

5-hydroxypentylamine

4-hydroxysalicylic acid

2,4-bis(benzyloxy)benzoic acid

Downstream raw materials:

Argiotoxin 636