5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Base Information

Chemical Name:5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide
CAS No.:647829-14-9
Molecular Formula:C₂₅H₂₁ClN₄O₃S
Molecular Weight:492.986
Hs Code.:

Synonyms:5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Suppliers and Price of 5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

There total 7 articles about 5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 647829-11-6
[5-Acetyl-4-(4-chloro-phenyl)-3-cyano-6-methyl-pyridin-2-ylsulfanyl]-acetic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

: 647829-14-9
5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Guidance literature:: With sodium ethanolate; In ethanol; for 0.0833333h; Heating;

Reference yield:

: 103868-29-7
5-acetyl-6-methyl-4-(4-chlorophenyl)-3-cyano-2<1H>pyridinethione

: 647829-14-9
5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / sodium acetate trihydrate / ethanol / 2 h / Heating

2: 96 percent / sodium ethoxide / ethanol / 0.08 h / Heating

3: hydrazine hydrate / ethanol / 6 h / Heating

4: ethanol / 1 h / Heating

With sodium ethanolate; sodium acetate; hydrazine hydrate; In ethanol; 2: Thorpe-Ziegler cyclization;

Reference yield:

: 647829-30-9
[5-acetyl-4-(4-chloro-phenyl)-3-cyano-6-methyl-pyridin-2-ylsulfanyl]-acetic acid ethyl ester

: 647829-14-9
5-Acetyl-3-amino-4-(4-chloro-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid [1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / sodium ethoxide / ethanol / 0.08 h / Heating

2: hydrazine hydrate / ethanol / 6 h / Heating

3: ethanol / 1 h / Heating

With sodium ethanolate; hydrazine hydrate; In ethanol; 1: Thorpe-Ziegler cyclization;