methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate

Base Information

• Chemical Name: methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate
• CAS No.: 314745-06-7
• Molecular Formula: C₁₈H₁₄O₆
• Molecular Weight: 326.306
• Mol file: 314745-06-7.mol

Synonyms:methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate

Chemical Property of methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate

There total 1 articles about methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5,7-dihydroxy-2-phenyl-chromen-4-one (480-40-0) + bromoacetic acid methyl ester (96-32-2) → methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate (314745-06-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 ℃; for 3h;

DOI:10.2147/DDDT.S189476

Reference yield: 99.0%

methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate (314745-06-7) → 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetic acid (97980-71-7)

Guidance literature:

With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.bmcl.2013.05.095

Reference yield: 98.0%

methyl 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate (314745-06-7) → 2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetohydrazide

Guidance literature:

With hydrazine; In ethanol; at 0 - 20 ℃; Solvent;

DOI:10.2147/DDDT.S189476

upstream raw materials:

5,7-dihydroxy-2-phenyl-chromen-4-one

bromoacetic acid methyl ester

Downstream raw materials:

N-(4-bromopyridin-2-yl)-2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetamide

2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)-N-(pyridin-2-yl)acetamide

N-(3-fluoropyridin-2-yl)-2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetamide

2-((5-hydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)-N-(m-tolyl)acetamide