4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester

Base Information

Chemical Name:4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester
CAS No.:1204316-03-9
Molecular Formula:C₂₁H₂₆ClN₃O₃
Molecular Weight:403.909
Hs Code.:

Synonyms:4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester

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Technology Process of 4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester

There total 1 articles about 4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22536-67-0
2,5-dichloropyrimidine

: 1204301-94-9
2-methyl-4-(3-piperidin-4-ylpropoxy)-benzoic acid methyl ester hydrochloride

: 1204316-03-9
4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dimethyl sulfoxide; at 100 ℃; for 16h;

Reference yield:

: 1204316-03-9
4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester

: 1204336-23-1
4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid

Guidance literature:: 4-{3-[1-(5-chloropyrimidin-2-yl)piperidin-4-yl]propoxy}-2-methylbenzoic acid methyl ester; With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 65 ℃; for 96h;

With sodium hydroxide;

With hydrogenchloride; In water; pH=1;