N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide)

Base Information

• Chemical Name: N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide)
• CAS No.: 1268611-39-7
• Molecular Formula: C₁₇H₂₀BrN₅O₂
• Molecular Weight: 406.282
• Mol file: 1268611-39-7.mol

Synonyms:N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide)

Chemical Property of N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide)

There total 2 articles about N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

isobutyryl chloride (79-30-1) + 6-(4-bromophenyl)-1,3,5-triazine-2,4-diamine (30508-74-8) → N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) (1268611-39-7)

Guidance literature:

With pyridine; for 72h; Reflux;

DOI:10.1016/j.jorganchem.2010.09.047

Reference yield:

4-bromobenzenecarbonitrile (623-00-7) → N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) (1268611-39-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / 2-ethoxy-ethanol / 24 h / Reflux

2: pyridine / 72 h / Reflux

With pyridine; potassium hydroxide; In 2-ethoxy-ethanol;

DOI:10.1016/j.jorganchem.2010.09.047

Reference yield: 78.0%

N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) (1268611-39-7) + trimethylsilylacetylene (1066-54-2) → N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) (1268611-43-3)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine; In tetrahydrofuran; at 50 ℃; for 72h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2010.09.047

upstream raw materials:

4-bromobenzenecarbonitrile

isobutyryl chloride

6-(4-bromophenyl)-1,3,5-triazine-2,4-diamine

Downstream raw materials:

N,N'-(6-(4-ethynylphenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide)

N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide)