30508-74-8

Usage

Uses

Used in Pharmaceutical Industry:
6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure allows for the creation of compounds with specific therapeutic properties, addressing unmet medical needs.
Used in Agrochemical Industry:
In the agrochemical industry, 6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE is used as a precursor in the development of novel agrochemicals. Its incorporation into these products can enhance their effectiveness in pest control and crop protection, contributing to increased agricultural productivity.
Used in Material Science:
6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE is utilized as a building block in the design of novel materials for various industrial and research purposes. Its unique chemical properties enable the creation of materials with specific characteristics, such as improved stability, reactivity, or selectivity, which can be applied in various technological applications.
Used in Organic Synthesis:
As a versatile chemical compound, 6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE is used in organic synthesis to create new chemical entities with potential applications in various industries. Its reactivity and structural features make it a valuable component in the synthesis of complex organic molecules, expanding the scope of chemical research and development.

InChI:InChI=1/C9H8BrN5/c10-6-3-1-5(2-4-6)7-13-8(11)15-9(12)14-7/h1-4H,(H4,11,12,13,14,15)

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 127099-85-8 N-Cyanoguanidine 

Downstream Products

• 1268611-38-6 N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)dipropionamide 
• 1268611-40-0 N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2,2-methylpropanamide) 
• 1268611-41-1 C₂₁H₂₈BrN₅O₂ 
• 1268611-39-7 N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) 
• 1268611-42-2 N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)dipropionamide 
• 1268611-43-3 N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) 
• 1268611-44-4 N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)bis(2,2-dimethylpropanamide) 
• 1268611-46-6 N,N'-(6-(4-ethynylphenyl)-1,3,5-triazine-2,4-diyl)dipropionamide 
• 1268611-47-7 N,N'-(6-(4-ethynylphenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) 
• 1268611-48-8 N,N'-(6-(4-ethynylphenyl)-1,3,5-triazine-2,4-diyl)bis(2,2-dimethylpropanamide) 
• 1268611-49-9 HCC(C₆H₄)C₃N₃(NHC(O)C₅H₁₁)2 

Relevant academic research and scientific papers

Covalent Functionalization of Carbon Nitride Frameworks through Cross-Coupling Reactions

A new and simple synthetic route is introduced to covalently functionalize the carbon nitride (CN) framework by the implementation of halogenated phenyl groups (Cl, Br and I), which serve as a chemically reactive center, within the CN framework. The coval

2,4,6-trisubstituted-1,3,5-s-triazine compound and preparation and application thereof

The invention provides a 2,4,6-trisubstituted-1,3,5-s-triazine compound as well as preparation and application thereof, and biguanide or dimethyl biguanide hydrochloride is used as an initial raw material to react with a cyano compound under an alkaline condition to prepare the 2,4,6-trisubstituted-1,3,5-s-triazine compound. The invention provides a simple and convenient synthetic method of a 2,4,6-trisubstituted-1,3,5-s-triazine compound, and the compound provided by the invention can be applied to preparation of an anti-myelogenous leukemia medicine, namely an enasidenib medicine. Compared with the prior art, the method for preparing the enasidenib has the advantages that two-step reaction is reduced, the use of a halogenating reagent is avoided, and the method is a green and environment-friendly chemical process. The structural formula I is shown in the specification.

Synthesis, molecular docking studies, and in vitro evaluation of 1,3,5-triazine derivatives as promising antimicrobial agents

The six-membered ring heterocycle 1,3,5-triazine and its derivatives have attracted considerable attention as they have proven to be excellent bioactive herbicides, cancer agents, etc. A series of 1,3,5-triazine derivatives (3a-o) were synthesized by a single step reaction and characterized by 1H NMR, 13C NMR, and mass spectrometry analysis. Antimicrobial screening of title compounds (3a-o) was examined against five bacterial and two fungal strains. In vitro study revealed that the freshly synthesized 6-(thiazol-4-yl)-1,3,5-triazine-2,4-diamine (3o) showed good antibacterial growth inhibition against E. coli, K. pneumoniae, and A. baumannii bacterial strains, and even the fungi C. neoformans. Molecular docking studies were performed on the X-ray crystal structure of E. coli 24 kDa domain in complex with clorobiocin (PDB code: 1KZN; resolution 2.30 ?) using Surflex-Dock program of Sybyl-X software. The results obtained are very encouraging.

Design of bis(acylamino)triazine containing ruthenium-acetylides as self-complementary supramolecular units

A series of systematically varied 'rigid-rod' octahedral ruthenium-acetylide complexes, bearing conjugated bis(acylamino)triazine (DAT) substituents capable of ADAD-DADA pairing, of general formula trans-[(dppe) 2Ru(Cl)(CC-C6H4