30508-74-8

Basic information

• Product Name: 6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE
• Synonyms: 2,4-DIAMINO-6-(4-BROMOPHENYL)-1,3,5-TRIAZINE;6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE;2,4-DIAMINO-6-(4-BROMOPHENYL)-1,3,5-TRI&;1,3,5-Triazine-2,4-diaMine, 6-(4-broMophenyl)-
• CAS NO: 30508-74-8
• Molecular Formula: C₉H₈BrN₅
• Molecular Weight: 266.1
• Product Categories: TriazinesBuilding Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Triazines
• Mol File: 30508-74-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 264-268 °C(lit.)
• Boiling Point: 528.8 °C at 760 mmHg
• Flash Point: 273.6 °C
• Appearance: /
• Density: 1.715 g/cm³
• Vapor Pressure: 2.87E-11mmHg at 25°C
• Refractive Index: 1.72
• PKA: 4.06±0.10(Predicted)
• CAS DataBase Reference: 6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE(30508-74-8)
• EPA Substance Registry System: 6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE(30508-74-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36-45
• Hazardous Substances Data: 30508-74-8(Hazardous Substances Data)

Usage

General Description

6-(4-Bromophenyl)-1,3,5-triazine-2,4-diamine is a chemical compound that belongs to the class of triazine-based compounds. It is a derivative of 1,3,5-triazine, containing a bromophenyl group. 6-(4-BROMOPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE may be used in the synthesis of various pharmaceuticals and agrochemicals, as well as in material science and organic synthesis. It has potential applications in the development of new drugs and in the design of novel materials for various industrial and research purposes. Additionally, it may also serve as a building block in the development of new chemical compounds with potential biological and industrial activities.

InChI:InChI=1/C9H8BrN5/c10-6-3-1-5(2-4-6)7-13-8(11)15-9(12)14-7/h1-4H,(H4,11,12,13,14,15)

Upstream product

• 623-00-7 4-bromobenzenecarbonitrile 
• 127099-85-8 N-Cyanoguanidine 

Downstream Products

• 1268611-38-6 N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)dipropionamide 
• 1268611-40-0 N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2,2-methylpropanamide) 
• 1268611-41-1 C₂₁H₂₈BrN₅O₂ 
• 1268611-39-7 N,N'-(6-(4-bromophenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) 
• 1268611-42-2 N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)dipropionamide 
• 1268611-43-3 N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) 
• 1268611-44-4 N,N'-(6-(4-((trimethylsilyl)ethynyl)phenyl)-1,3,5-triazine-2,4-diyl)bis(2,2-dimethylpropanamide) 
• 1268611-46-6 N,N'-(6-(4-ethynylphenyl)-1,3,5-triazine-2,4-diyl)dipropionamide 
• 1268611-47-7 N,N'-(6-(4-ethynylphenyl)-1,3,5-triazine-2,4-diyl)bis(2-methylpropanamide) 
• 1268611-48-8 N,N'-(6-(4-ethynylphenyl)-1,3,5-triazine-2,4-diyl)bis(2,2-dimethylpropanamide) 
• 1268611-49-9 HCC(C₆H₄)C₃N₃(NHC(O)C₅H₁₁)2 

Relevant articles and documents

Covalent Functionalization of Carbon Nitride Frameworks through Cross-Coupling Reactions

A new and simple synthetic route is introduced to covalently functionalize the carbon nitride (CN) framework by the implementation of halogenated phenyl groups (Cl, Br and I), which serve as a chemically reactive center, within the CN framework. The coval

Synthesis, molecular docking studies, and in vitro evaluation of 1,3,5-triazine derivatives as promising antimicrobial agents

The six-membered ring heterocycle 1,3,5-triazine and its derivatives have attracted considerable attention as they have proven to be excellent bioactive herbicides, cancer agents, etc. A series of 1,3,5-triazine derivatives (3a-o) were synthesized by a single step reaction and characterized by 1H NMR, 13C NMR, and mass spectrometry analysis. Antimicrobial screening of title compounds (3a-o) was examined against five bacterial and two fungal strains. In vitro study revealed that the freshly synthesized 6-(thiazol-4-yl)-1,3,5-triazine-2,4-diamine (3o) showed good antibacterial growth inhibition against E. coli, K. pneumoniae, and A. baumannii bacterial strains, and even the fungi C. neoformans. Molecular docking studies were performed on the X-ray crystal structure of E. coli 24 kDa domain in complex with clorobiocin (PDB code: 1KZN; resolution 2.30 ?) using Surflex-Dock program of Sybyl-X software. The results obtained are very encouraging.