1⁴,4⁴-diiodo-1³,2³,3²,4³-tetramethoxy-p-quarterphenyl

Base Information

• Chemical Name: 1⁴,4⁴-diiodo-1³,2³,3²,4³-tetramethoxy-p-quarterphenyl
• CAS No.: 195737-42-9
• Molecular Formula: C₂₈H₂₄I₂O₄
• Molecular Weight: 678.305
• Mol file: 195737-42-9.mol

Synonyms:1⁴,4⁴-diiodo-1³,2³,3²,4³-tetramethoxy-p-quarterphenyl

Chemical Property of 1⁴,4⁴-diiodo-1³,2³,3²,4³-tetramethoxy-p-quarterphenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1⁴,4⁴-diiodo-1³,2³,3²,4³-tetramethoxy-p-quarterphenyl

There total 5 articles about 1⁴,4⁴-diiodo-1³,2³,3²,4³-tetramethoxy-p-quarterphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

13,23,32,43-tetramethoxy-p-quarterphenyl (4499-73-4) → 14,44-diiodo-13,23,32,43-tetramethoxy-p-quarterphenyl (195737-42-9)

Guidance literature:

1³,2³,3²,4³-tetramethoxy-p-quarterphenyl; With tert.-butyl lithium; In toluene; pentane; at 0 - 20 ℃; for 2.5h;

With iodine; In diethyl ether; toluene; pentane; at 20 ℃; Further stages.;

DOI:10.1021/ol016914n

Reference yield:

3,3'-dimethoxybiphenyl (6161-50-8) → 14,44-diiodo-13,23,32,43-tetramethoxy-p-quarterphenyl (195737-42-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 34 percent / t-BuLi, I₂ / diethyl ether

2: 64 percent / n-BuLi, CuCl₂

3: 29 percent / t-BuLi, I₂

With n-butyllithium; iodine; tert.-butyl lithium; copper dichloride; In diethyl ether;

DOI:10.1021/ja971513h

Reference yield:

4-iodo-3,3'-dimethoxy-1,1'-biphenyl (108541-94-2) → 14,44-diiodo-13,23,32,43-tetramethoxy-p-quarterphenyl (195737-42-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi

1.2: 64 percent / CuCl₂

2.1: t-BuLi / toluene; pentane / 2.5 h / 0 - 20 °C

2.2: 46 percent / I₂ / toluene; pentane; diethyl ether / 20 °C

With n-butyllithium; tert.-butyl lithium; In toluene; pentane;

DOI:10.1021/ol016914n

upstream raw materials:

1³,2³,3²,4³-tetramethoxy-p-quarterphenyl

4,4'-diiodo-3,3'-dimethoxylbiphenyl

4-iodo-3,3'-dimethoxy-1,1'-biphenyl

fast blue B

Downstream raw materials:

C₅₆H₅₀O₈

1³,2³,3²,4³,5²,6³,7²,8³-octahydroxy-p-octiphenyl

2,2',2'',2'''-[(4,4'-diiodo-[1,1':4',1:4,1'-quaterpenyl]-2,3,3',3'-tetrayl)tetrakis(oxy)]tetrakis[acetic acid] tetra(tert-butyl ester)