2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

Base Information

Chemical Name:2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester
CAS No.:608510-43-6
Molecular Formula:C₃₈H₆₃NO₄Si
Molecular Weight:626.008
Hs Code.:

2-({2-[3-(<i>tert</i>-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

Synonyms:2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

Suppliers and Price of 2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

There total 9 articles about 2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 608510-42-5
(S)-2-{[2-(2,3-Dihydroxy-propyl)-phenyl]-undecyl-amino}-3-methyl-butyric acid benzyl ester

: 608510-43-6
2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00637-1

Reference yield:

: 211935-16-9
3-(2-Nitro-phenyl)-propane-1,2-diol

: 608510-43-6
2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: pyridine

2: H₂ / Pd/C / ethanol

3: 99 percent / Et₃N / tetrahydrofuran

4: BH₃ / tetrahydrofuran

5: NaOH / methanol

6: 76 percent / 2,6-lutidine / 1,2-dichloro-ethane

7: 91 percent / imidazole / dimethylformamide

With pyridine; 1H-imidazole; 2,6-dimethylpyridine; sodium hydroxide; borane; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00637-1

Reference yield:

: acetic acid 1-acetoxymethyl-2-(2-nitro-phenyl)-ethyl ester

: 608510-43-6
2-({2-[3-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-propyl]-phenyl}-undecyl-amino)-3-methyl-butyric acid benzyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: H₂ / Pd/C / ethanol

2: 99 percent / Et₃N / tetrahydrofuran

3: BH₃ / tetrahydrofuran

4: NaOH / methanol

5: 76 percent / 2,6-lutidine / 1,2-dichloro-ethane

6: 91 percent / imidazole / dimethylformamide

With 1H-imidazole; 2,6-dimethylpyridine; sodium hydroxide; borane; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00637-1