2-(2,6-dichlorophenyl)butanoic Acid

Base Information

Chemical Name:2-(2,6-dichlorophenyl)butanoic Acid
CAS No.:359828-69-6
Molecular Formula:C₁₀H₁₀Cl₂O₂
Molecular Weight:233.094
Hs Code.:
DSSTox Substance ID:DTXSID001284655

Synonyms:2-(2,6-dichlorophenyl)butanoic Acid;359828-69-6;Benzeneacetic acid, 2,6-dichloro-alpha-ethyl-;DTXSID001284655;2,6-Dichloro-alpha-ethylbenzeneacetic acid;E86012;EN300-1968453

Suppliers and Price of 2-(2,6-dichlorophenyl)butanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-(2,6-dichlorophenyl)butanoic Acid

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:232.0057849
Heavy Atom Count:14
Complexity:198

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(C1=C(C=CC=C1Cl)Cl)C(=O)O

Technology Process of 2-(2,6-dichlorophenyl)butanoic Acid

There total 1 articles about 2-(2,6-dichlorophenyl)butanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 6575-24-2
2-(2,6-dichlorophenyl)acetic acid

: 75-03-6
ethyl iodide

: 359828-69-6
2-(2,6-dichloro-phenyl)-butyric acid

Guidance literature:: 2-(2,6-dichlorophenyl)acetic acid; With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at 20 ℃; for 0.5h;

ethyl iodide; In tetrahydrofuran; n-heptane; ethylbenzene; at 20 ℃; for 0.0833333h; Further stages.;
DOI:10.1021/jm010853h

Reference yield:

: 359828-69-6
2-(2,6-dichloro-phenyl)-butyric acid

: 359828-77-6
4-(2,6-dichloro-phenyl)-3-oxo-hexanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetonitrile

2.1: Et₃N; MgCl₂ / acetonitrile / 2 h / 20 °C

2.2: acetonitrile / 2 h / Heating

2.3: 89 percent / 13percent aq. HCl / acetonitrile / 0.25 h

With triethylamine; magnesium chloride; In acetonitrile;
DOI:10.1021/jm010853h

Reference yield:

: 359828-69-6
2-(2,6-dichloro-phenyl)-butyric acid

: 359828-84-5
6-[1-(2,6-dichloro-phenyl)-propyl]-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetonitrile

2.1: Et₃N; MgCl₂ / acetonitrile / 2 h / 20 °C

2.2: acetonitrile / 2 h / Heating

2.3: 89 percent / 13percent aq. HCl / acetonitrile / 0.25 h

3.1: 61 percent / NaOEt / ethanol / 5 h / Heating

With sodium ethanolate; triethylamine; magnesium chloride; In ethanol; acetonitrile;
DOI:10.1021/jm010853h