2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole

Base Information

• Chemical Name: 2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole
• CAS No.: 159350-46-6
• Molecular Formula: C₁₀H₁₁N₃O₄S
• Molecular Weight: 269.281
• Mol file: 159350-46-6.mol

Synonyms:2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole

Chemical Property of 2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole

Chemical Property:

Purity/Quality:

2-METHYL-1-[(4-NITROPHENYL)SULFONYL]-4,5-DIHYDRO-1H-IMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole

There total 1 articles about 2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

lysidine (534-26-9) + 4-Nitrobenzenesulfonyl chloride (98-74-8) → 2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole (159350-46-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1081/SCC-120003643

Reference yield: 90.0%

2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole (159350-46-6) + methyl iodide (74-88-4) → 1,2-dimethyl-3-(4-nitro-benzenesulfonyl)-4,5-dihydro-3H-imidazol-1-ium; iodide

Guidance literature:

In dichloromethane; Heating;

DOI:10.1081/SCC-120003643

Reference yield:

2-methyl-1-(4-nitro-benzenesulfonyl)-4,5-dihydro-1H-imidazole (159350-46-6) → N-[2-(ethyl-methyl-amino)-ethyl]-4-nitro-benzenesulfonamide

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / CH₂Cl₂ / Heating

2: 85 percent / NaBH₄ / ethanol / 20 °C

With sodium tetrahydroborate; In ethanol; dichloromethane;

DOI:10.1081/SCC-120003643

upstream raw materials:

lysidine

4-Nitrobenzenesulfonyl chloride