4-[(methoxycarbonyl)methyl]phenyl mesylate

Base Information

• Chemical Name: 4-[(methoxycarbonyl)methyl]phenyl mesylate
• CAS No.: 539814-10-3
• Molecular Formula: C₁₀H₁₂O₅S
• Molecular Weight: 244.268
• Mol file: 539814-10-3.mol

Synonyms:4-[(methoxycarbonyl)methyl]phenyl mesylate

Chemical Property of 4-[(methoxycarbonyl)methyl]phenyl mesylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[(methoxycarbonyl)methyl]phenyl mesylate

There total 2 articles about 4-[(methoxycarbonyl)methyl]phenyl mesylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

Methyl 4-hydroxyphenylacetate (14199-15-6) + methanesulfonyl chloride (124-63-0) → 4-[(methoxycarbonyl)methyl]phenyl mesylate (539814-10-3)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/ol060045q

Reference yield: 77.0%

→ 4-[(methoxycarbonyl)methyl]phenyl mesylate (539814-10-3)

Guidance literature:

Reference yield: 98.0%

4-[(methoxycarbonyl)methyl]phenyl mesylate (539814-10-3) → benzeneacetic acid methyl ester (101-41-7)

Guidance literature:

With ammonium acetate; magnesium; palladium on activated charcoal; In methanol; at 20 ℃; for 12h;

DOI:10.1021/ol060045q

upstream raw materials:

Methyl 4-hydroxyphenylacetate

methanesulfonyl chloride

Downstream raw materials:

benzeneacetic acid methyl ester

methyl 2-(4-methylsulfonyloxyphenyl)acetic acid

4-methanesulfonyloxy-benzoic acid 4-{2-carboxy-2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-ethyl}-benzyl ester

C₂₈H₂₆Cl₃FO₇S₂

Refernces

• 1、 Mori, Akinori,Mizusaki, Tomoteru,Ikawa, Takashi,Maegawa, Tomohiro,Monguchi, Yasunari,Sajiki, Hironao. "Palladium on carbon-diethylamine-mediated hydrodeoxygenation of phenol derivatives under mild conditions". . p. 1270 - 1280. Retrieved 2007/10/03.
• 2、 -. "Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them". Page 23. . Retrieved 2008/06/13.