Technology Process of ethyl 2-[4-(2-ethoxy-2-hydroxyethyl)-2,5-dimethylphenoxy]acetate
There total 6 articles about ethyl 2-[4-(2-ethoxy-2-hydroxyethyl)-2,5-dimethylphenoxy]acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
ethyl 2-[4-(2,2-dimethoxyethyl)-2,5-dimethylphenoxy]acetate;
With
perchloric acid; water;
In
acetonitrile;
at 20 ℃;
for 1h;
ethanol;
ethanol;
In
hexane;
at 0 - 10 ℃;
for 4h;
- Guidance literature:
-
ethyl 2-[4-(2,2-dimethoxyethyl)-2,5-dimethylphenoxy]acetate;
With
oxalic acid;
In
water; acetonitrile;
at 42 ℃;
for 3h;
Large scale;
With
potassium carbonate;
In
tert-butyl methyl ether; water; toluene; acetonitrile;
at 26 - 30 ℃;
Large scale;
DOI:10.1021/acs.oprd.0c00278
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate; sodium iodide / N,N-dimethyl-formamide / 3 h / 60 °C / Large scale
2.1: sodium iodide; chloro-trimethyl-silane / acetonitrile / 1.38 h / -19 - -18 °C / Large scale
2.2: 0.42 h / -17 - -9 °C / Large scale
2.3: 1.17 h / -9 - 15 °C / Large scale
3.1: oxalic acid / water; acetonitrile / 3 h / 42 °C / Large scale
3.2: 26 - 30 °C / Large scale
With
chloro-trimethyl-silane; oxalic acid; potassium carbonate; sodium iodide;
In
water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/acs.oprd.0c00278
![ethyl 2-[4-(2,2-dimethoxyethyl)-2,5-dimethylphenoxy]acetate](/Databaselist/images/loading.webp)
