4,7-Dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester

Base Information

• Chemical Name: 4,7-Dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester
• CAS No.: 79970-23-3
• Molecular Formula: C₁₅H₁₄N₂O₈S
• Molecular Weight: 382.351

Synonyms:4,7-Dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester

Chemical Property of 4,7-Dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,7-Dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester

There total 5 articles about 4,7-Dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

Chloro-(2-methoxycarbonylmethanesulfinyl-4-oxo-azetidin-1-yl)-acetic acid 4-nitro-benzyl ester (79970-22-2) → 4,7-Dioxo-4λ4-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester (79970-23-3)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1021/jo00340a044

Reference yield:

Methyl α<(2R*)-4-Oxoazetidin-2-ylthio>acetate (31898-76-7) → 4,7-Dioxo-4λ4-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester (79970-23-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 92 percent / benzene / 12 h / Heating

2: 100 percent / SOCl₂, lutidine / CH₂Cl₂ / 0 °C

3: 75 percent / m-chloroperbenzoic acid / CH₂Cl₂

4: 53 percent / lithium diisopropyl amide / tetrahydrofuran / -78 °C

With thionyl chloride; lutidine; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; benzene;

DOI:10.1021/jo00340a044

Reference yield:

p-nitrobenzyl glyoxylate (64370-35-0) → 4,7-Dioxo-4λ4-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester (79970-23-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 92 percent / benzene / 12 h / Heating

2: 100 percent / SOCl₂, lutidine / CH₂Cl₂ / 0 °C

3: 75 percent / m-chloroperbenzoic acid / CH₂Cl₂

4: 53 percent / lithium diisopropyl amide / tetrahydrofuran / -78 °C

With thionyl chloride; lutidine; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; benzene;

DOI:10.1021/jo00340a044

upstream raw materials:

Chloro-(2-methoxycarbonylmethanesulfinyl-4-oxo-azetidin-1-yl)-acetic acid 4-nitro-benzyl ester

Methyl α<(2R*)-4-Oxoazetidin-2-ylthio>acetate

p-nitrobenzyl glyoxylate

Hydroxy-(2-methoxycarbonylmethylsulfanyl-4-oxo-azetidin-1-yl)-acetic acid 4-nitro-benzyl ester

Downstream raw materials:

7-Oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 79970-23-3 4,7-Dioxo-4λ⁴-thia-1-aza-bicyclo[3.2.0]heptane-2,3-dicarboxylic acid 3-methyl ester 2-(4-nitro-benzyl) ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send