3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

Base Information

Chemical Name:3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester
CAS No.:1342302-06-0
Molecular Formula:C₂₅H₃₅NO₆
Molecular Weight:445.556
Hs Code.:

Synonyms:3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

Suppliers and Price of 3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

There total 6 articles about 3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 591-87-7
Allyl acetate

: 1342302-05-9
(1S)-(2-formylcyclohex-2-enyl)(4-methoxybenzyl)carbamic acid tert-butyl ester

: 1342302-06-0
3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

Guidance literature:: Allyl acetate; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

(1S)-(2-formylcyclohex-2-enyl)(4-methoxybenzyl)carbamic acid tert-butyl ester; In tetrahydrofuran; hexane; at -78 ℃; for 12h;
DOI:10.1055/s-0030-1260102

Reference yield:

: 932743-56-1
(6S)-6-(4-methoxybenzylamino)cyclohex-1-enecarboxylic acid methyl ester

: 1342302-06-0
3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine; sodium iodide / acetonitrile / 0 - 20 °C

2.1: diisobutylaluminium hydride / hexane; dichloromethane / 0.5 h / -78 °C

3.1: Dess-Martin periodane; triethylamine / dichloromethane / 4 h / 20 °C

4.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.5 h / -78 °C

4.2: 12 h / -78 °C

With diisobutylaluminium hydride; Dess-Martin periodane; triethylamine; sodium iodide; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane; acetonitrile; 3.1: Dess-Martin oxidation;
DOI:10.1055/s-0030-1260102

Reference yield:

: 1342302-22-0
C₂₀H₂₉NO₄

: 1342302-06-0
3-{(6S)-6-[tert-butoxycarbonyl(4-methoxybenzyl)amino]cyclohex-1-enyl}-3-hydroxypropionic acid allyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: Dess-Martin periodane; triethylamine / dichloromethane / 4 h / 20 °C

2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: 12 h / -78 °C

With Dess-Martin periodane; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane; 1.1: Dess-Martin oxidation;
DOI:10.1055/s-0030-1260102